Emerging techniques in atherosclerosis imaging

Atherosclerosis is a chronic immunomodulated disease that affects multiple vascular beds and results in a significant worldwide disease burden. Conventional imaging modalities focus on the morphological features of atherosclerotic disease such as the degree of stenosis caused by a lesion. Modern CT,...

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Main Authors: Maaz B.J. Syed, Alexander J. Fletcher, Rachael O. Forsythe, Jakub Kaczynski, David E. Newby, Marc R. Dweck, Edwin J. R. van Beek
Format: Article
Language:English
Published: Eco-Vector 2021-10-01
Series:Digital Diagnostics
Subjects:
Online Access:https://jdigitaldiagnostics.com/DD/article/viewFile/71633/pdf
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author Maaz B.J. Syed
Alexander J. Fletcher
Rachael O. Forsythe
Jakub Kaczynski
David E. Newby
Marc R. Dweck
Edwin J. R. van Beek
author_facet Maaz B.J. Syed
Alexander J. Fletcher
Rachael O. Forsythe
Jakub Kaczynski
David E. Newby
Marc R. Dweck
Edwin J. R. van Beek
author_sort Maaz B.J. Syed
collection DOAJ
description Atherosclerosis is a chronic immunomodulated disease that affects multiple vascular beds and results in a significant worldwide disease burden. Conventional imaging modalities focus on the morphological features of atherosclerotic disease such as the degree of stenosis caused by a lesion. Modern CT, MR and positron emission tomography scanners have seen significant improvements in the rapidity of image acquisition and spatial resolution. This has increased the scope for the clinical application of these modalities. Multimodality imaging can improve cardiovascular risk prediction by informing on the constituency and metabolic processes within the vessel wall. Specific disease processes can be targeted using novel biological tracers and smart contrast agents. These approaches have the potential to inform clinicians of the metabolic state of atherosclerotic plaque. This review will provide an overview of current imaging techniques for the imaging of atherosclerosis and how various modalities can provide information that enhances the depiction of basic morphology. This publication is the reprint with Russian translation from original: Syed MB, Fletcher AJ, Forsythe RO, Kaczynski J, Newby DE, Dweck MR, van Beek EJ. Emerging techniques in atherosclerosis imaging. Br J Radiol. 2019;92(1103):20180309. doi: 10.1259/bjr.20180309.
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spelling doaj.art-944f89ac868b42e0a169cbb0a0e6d7e32022-12-21T23:30:36ZengEco-VectorDigital Diagnostics2712-84902712-89622021-10-012338640910.17816/DD7163365519Emerging techniques in atherosclerosis imagingMaaz B.J. Syed0https://orcid.org/0000-0003-0530-8306Alexander J. Fletcher1https://orcid.org/0000-0001-9984-8391Rachael O. Forsythe2https://orcid.org/0000-0002-3311-9599Jakub Kaczynski3https://orcid.org/0000-0002-3005-6860David E. Newby4https://orcid.org/0000-0001-7971-4628Marc R. Dweck5https://orcid.org/0000-0001-9847-5917Edwin J. R. van Beek6https://orcid.org/0000-0002-2777-5071University of EdinburghUniversity of EdinburghUniversity of EdinburghUniversity of EdinburghUniversity of EdinburghUniversity of EdinburghUniversity of EdinburghAtherosclerosis is a chronic immunomodulated disease that affects multiple vascular beds and results in a significant worldwide disease burden. Conventional imaging modalities focus on the morphological features of atherosclerotic disease such as the degree of stenosis caused by a lesion. Modern CT, MR and positron emission tomography scanners have seen significant improvements in the rapidity of image acquisition and spatial resolution. This has increased the scope for the clinical application of these modalities. Multimodality imaging can improve cardiovascular risk prediction by informing on the constituency and metabolic processes within the vessel wall. Specific disease processes can be targeted using novel biological tracers and smart contrast agents. These approaches have the potential to inform clinicians of the metabolic state of atherosclerotic plaque. This review will provide an overview of current imaging techniques for the imaging of atherosclerosis and how various modalities can provide information that enhances the depiction of basic morphology. This publication is the reprint with Russian translation from original: Syed MB, Fletcher AJ, Forsythe RO, Kaczynski J, Newby DE, Dweck MR, van Beek EJ. Emerging techniques in atherosclerosis imaging. Br J Radiol. 2019;92(1103):20180309. doi: 10.1259/bjr.20180309.https://jdigitaldiagnostics.com/DD/article/viewFile/71633/pdfatherosclerosisultrasound diagnosticsradiologymagnetic resonance imagingpositron emission tomographycardiovascular riskoptical coherence tomographymolecular imaging
spellingShingle Maaz B.J. Syed
Alexander J. Fletcher
Rachael O. Forsythe
Jakub Kaczynski
David E. Newby
Marc R. Dweck
Edwin J. R. van Beek
Emerging techniques in atherosclerosis imaging
Digital Diagnostics
atherosclerosis
ultrasound diagnostics
radiology
magnetic resonance imaging
positron emission tomography
cardiovascular risk
optical coherence tomography
molecular imaging
title Emerging techniques in atherosclerosis imaging
title_full Emerging techniques in atherosclerosis imaging
title_fullStr Emerging techniques in atherosclerosis imaging
title_full_unstemmed Emerging techniques in atherosclerosis imaging
title_short Emerging techniques in atherosclerosis imaging
title_sort emerging techniques in atherosclerosis imaging
topic atherosclerosis
ultrasound diagnostics
radiology
magnetic resonance imaging
positron emission tomography
cardiovascular risk
optical coherence tomography
molecular imaging
url https://jdigitaldiagnostics.com/DD/article/viewFile/71633/pdf
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AT rachaeloforsythe emergingtechniquesinatherosclerosisimaging
AT jakubkaczynski emergingtechniquesinatherosclerosisimaging
AT davidenewby emergingtechniquesinatherosclerosisimaging
AT marcrdweck emergingtechniquesinatherosclerosisimaging
AT edwinjrvanbeek emergingtechniquesinatherosclerosisimaging