Generation of Haploid Spermatids with Fertilization and Development Capacity from Human Spermatogonial Stem Cells of Cryptorchid Patients

Generation of Haploid Spermatids with Fertilization and Development Capacity from Human Spermatogonial Stem Cells of Cryptorchid Patients

Generation of functional spermatids from azoospermia patients is of unusual significance in the treatment of male infertility. Here, we report an efficient approach to obtain human functional spermatids from cryptorchid patients. Spermatogonia remained whereas meiotic germ cells were rare in cryptor...

Full description

Bibliographic Details
Main Authors: Shi Yang, Ping Ping, Meng Ma, Peng Li, Ruhui Tian, Hao Yang, Yang Liu, Yuehua Gong, Zhenzhen Zhang, Zheng Li, Zuping He
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114002586

Similar Items

Similar Items