A tumor microenvironment-based prognostic index for osteosarcoma

A tumor microenvironment-based prognostic index for osteosarcoma

Abstract Background The tumor microenvironment (TME) has a central role in the oncogenesis of osteosarcomas. The composition of the TME is essential for the interaction between tumor and immune cells. The aim of this study was to establish a prognostic index (TMEindex) for osteosarcoma based on the...

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Bibliographic Details
Main Authors: Changwu Wu, Siming Gong, Yingjuan Duan, Chao Deng, Sonja Kallendrusch, Laura Berninghausen, Georg Osterhoff, Nikolas Schopow
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Journal of Biomedical Science
Subjects:
Osteosarcoma
Tumor microenvironment
Prognostic index
Checkpoint inhibitor therapy
Immune cell infiltration
Big data
Online Access:https://doi.org/10.1186/s12929-023-00917-3

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