Investigation of the Pathogenic Mechanism of Ciprofloxacin in Aortic Aneurysm and Dissection by an Integrated Proteomics and Network Pharmacology Strategy

Investigation of the Pathogenic Mechanism of Ciprofloxacin in Aortic Aneurysm and Dissection by an Integrated Proteomics and Network Pharmacology Strategy

Aortic aneurysm and dissection (AAD) is a life-threatening disease worldwide. Recently, fluoroquinolones have been reported to significantly increase the risk of AAD. This study aimed to investigate the potential functional mechanism and molecular targets of fluoroquinolones in relation to AAD by an...

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Bibliographic Details
Main Authors: Zhaoran Chen, Jianqiang Wu, Wei Wang, Xiaoyue Tang, Lei Zhou, Yanze Lv, Yuehong Zheng
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Clinical Medicine
Subjects:
aortic aneurysm and dissection
fluoroquinolones
proteomics
network pharmacology
molecular docking
Online Access:https://www.mdpi.com/2077-0383/12/4/1270

Internet

https://www.mdpi.com/2077-0383/12/4/1270

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