Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors
We retrospectively reviewed 28 patients (15 women and 13 men) with benign bone tumors or pseudotumors treated with curettage and filling with freeze-dried bovine bone graft Orthogen (Baumer S/A, São Paulo, Brazil). The aim of the study was to evaluate the rate of incorporation of Orthogen into the h...
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MDPI AG
2023-03-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/3/789 |
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| author | Priscilla Montanhini Bruno P. Antunes Julie Francine Cerutti Pestilho Carlos Roberto Galia Alex Guedes Ricardo Gehrke Becker |
| author_facet | Priscilla Montanhini Bruno P. Antunes Julie Francine Cerutti Pestilho Carlos Roberto Galia Alex Guedes Ricardo Gehrke Becker |
| author_sort | Priscilla Montanhini |
| collection | DOAJ |
| description | We retrospectively reviewed 28 patients (15 women and 13 men) with benign bone tumors or pseudotumors treated with curettage and filling with freeze-dried bovine bone graft Orthogen (Baumer S/A, São Paulo, Brazil). The aim of the study was to evaluate the rate of incorporation of Orthogen into the host bone, as well as to describe the outcomes of bone healing (quality, time, and complications). General characteristics, tumor volume, size, site, complications, percent filled, and healing quality at 6 and 12 months were assessed through radiographs. Mean patient age was 20.5 (range 4.7–75.1) years. The most common lesion type was simple bone cyst (12/28), and the most common sites were the tibia (7/28) and humerus (7/28). There were no postoperative pathologic fractures. Two cases (7.1%) of serous fluid leakage through the wound occurred. Mean cavity volume was 20.1 (range 2.7–101.4) cm<sup>3</sup>. At 6 and 12 months, 75% and 77.8% of cavities, respectively, showed complete bone healing. At 12 months, 81% of cavities filled >90% with graft showed complete bone healing vs. only 19% of those filled <90%. Filling with bovine bone graft resulted in few complications and excellent healing after curettage of benign bone tumors or pseudotumors. Complete healing occurred in most cases by 12 months. Cavities with a higher percentage of filling had a higher rate of complete radiographic incorporation. |
| first_indexed | 2024-03-11T06:17:24Z |
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| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-11T06:17:24Z |
| publishDate | 2023-03-01 |
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| record_format | Article |
| series | Life |
| spelling | doaj.art-9456a7ed9f0140b3a4d88ffa0cb533352023-11-17T12:12:23ZengMDPI AGLife2075-17292023-03-0113378910.3390/life13030789Bovine Grafting: An Effective Alternative after Curettage of Benign Bone TumorsPriscilla Montanhini0Bruno P. Antunes1Julie Francine Cerutti Pestilho2Carlos Roberto Galia3Alex Guedes4Ricardo Gehrke Becker5Hospital de Clínicas de Porto Alegre (HCPA), Rua Ramiro Barcelos, 2350, Porto Alegre 90035-903, RS, BrazilHospital de Clínicas de Porto Alegre (HCPA), Rua Ramiro Barcelos, 2350, Porto Alegre 90035-903, RS, BrazilInstituto do Câncer Infantil do Rio Grande do Sul, Rua São Manoel, 850, Porto Alegre 90620-110, RS, BrazilHospital de Clínicas de Porto Alegre (HCPA), Rua Ramiro Barcelos, 2350, Porto Alegre 90035-903, RS, BrazilHospital Santa Izabel, Praça Conselheiro Almeida Couto, 500, Salvador 40050-410, BA, BrazilHospital de Clínicas de Porto Alegre (HCPA), Rua Ramiro Barcelos, 2350, Porto Alegre 90035-903, RS, BrazilWe retrospectively reviewed 28 patients (15 women and 13 men) with benign bone tumors or pseudotumors treated with curettage and filling with freeze-dried bovine bone graft Orthogen (Baumer S/A, São Paulo, Brazil). The aim of the study was to evaluate the rate of incorporation of Orthogen into the host bone, as well as to describe the outcomes of bone healing (quality, time, and complications). General characteristics, tumor volume, size, site, complications, percent filled, and healing quality at 6 and 12 months were assessed through radiographs. Mean patient age was 20.5 (range 4.7–75.1) years. The most common lesion type was simple bone cyst (12/28), and the most common sites were the tibia (7/28) and humerus (7/28). There were no postoperative pathologic fractures. Two cases (7.1%) of serous fluid leakage through the wound occurred. Mean cavity volume was 20.1 (range 2.7–101.4) cm<sup>3</sup>. At 6 and 12 months, 75% and 77.8% of cavities, respectively, showed complete bone healing. At 12 months, 81% of cavities filled >90% with graft showed complete bone healing vs. only 19% of those filled <90%. Filling with bovine bone graft resulted in few complications and excellent healing after curettage of benign bone tumors or pseudotumors. Complete healing occurred in most cases by 12 months. Cavities with a higher percentage of filling had a higher rate of complete radiographic incorporation.https://www.mdpi.com/2075-1729/13/3/789bone graftingbiocompatible materialsbone substitutexenograftsbone neoplasmsbone cysts |
| spellingShingle | Priscilla Montanhini Bruno P. Antunes Julie Francine Cerutti Pestilho Carlos Roberto Galia Alex Guedes Ricardo Gehrke Becker Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors Life bone grafting biocompatible materials bone substitute xenografts bone neoplasms bone cysts |
| title | Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors |
| title_full | Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors |
| title_fullStr | Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors |
| title_full_unstemmed | Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors |
| title_short | Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors |
| title_sort | bovine grafting an effective alternative after curettage of benign bone tumors |
| topic | bone grafting biocompatible materials bone substitute xenografts bone neoplasms bone cysts |
| url | https://www.mdpi.com/2075-1729/13/3/789 |
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