Renal Medullary Carcinoma with an Aggressive Clinical Course: A Case Report and Review of the Literature
Renal medullary carcinoma (RMC) is a rare, yet aggressive malignancy of the kidney that is found predominantly in young patients with African descent and sickle cell hemoglobinopathies and most specifically sickle cell trait. Due to its aggressive nature, most cases have metastasis or local invasion...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2017-01-01
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| Series: | Case Reports in Oncology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/455007 |
| _version_ | 1818136697320243200 |
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| author | Madhumati R. Kalavar Sami Ali Damoun Safarpour Saroj Davi Kunnakkat |
| author_facet | Madhumati R. Kalavar Sami Ali Damoun Safarpour Saroj Davi Kunnakkat |
| author_sort | Madhumati R. Kalavar |
| collection | DOAJ |
| description | Renal medullary carcinoma (RMC) is a rare, yet aggressive malignancy of the kidney that is found predominantly in young patients with African descent and sickle cell hemoglobinopathies and most specifically sickle cell trait. Due to its aggressive nature, most cases have metastasis or local invasion at the time of diagnosis. Prognosis is extremely poor with survival less than 1 year after diagnosis. Here we present a case of metastatic RMC in a 29-year-old African female. Despite chemotherapy with cisplatin, gemcitabine, and paclitaxel, and initial shrinkage of the tumor, the patient died 5 months after diagnosis. |
| first_indexed | 2024-12-11T09:44:31Z |
| format | Article |
| id | doaj.art-9456be4585ee4243a4fed13b4af77c14 |
| institution | Directory Open Access Journal |
| issn | 1662-6575 |
| language | English |
| last_indexed | 2024-12-11T09:44:31Z |
| publishDate | 2017-01-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj.art-9456be4585ee4243a4fed13b4af77c142022-12-22T01:12:36ZengKarger PublishersCase Reports in Oncology1662-65752017-01-011011710.1159/000455007455007Renal Medullary Carcinoma with an Aggressive Clinical Course: A Case Report and Review of the LiteratureMadhumati R. KalavarSami AliDamoun SafarpourSaroj Davi KunnakkatRenal medullary carcinoma (RMC) is a rare, yet aggressive malignancy of the kidney that is found predominantly in young patients with African descent and sickle cell hemoglobinopathies and most specifically sickle cell trait. Due to its aggressive nature, most cases have metastasis or local invasion at the time of diagnosis. Prognosis is extremely poor with survival less than 1 year after diagnosis. Here we present a case of metastatic RMC in a 29-year-old African female. Despite chemotherapy with cisplatin, gemcitabine, and paclitaxel, and initial shrinkage of the tumor, the patient died 5 months after diagnosis.http://www.karger.com/Article/FullText/455007African descentSickle cell anemiaSickle cell traitKidney tumorRenal medullary carcinomaMetastasis |
| spellingShingle | Madhumati R. Kalavar Sami Ali Damoun Safarpour Saroj Davi Kunnakkat Renal Medullary Carcinoma with an Aggressive Clinical Course: A Case Report and Review of the Literature Case Reports in Oncology African descent Sickle cell anemia Sickle cell trait Kidney tumor Renal medullary carcinoma Metastasis |
| title | Renal Medullary Carcinoma with an Aggressive Clinical Course: A Case Report and Review of the Literature |
| title_full | Renal Medullary Carcinoma with an Aggressive Clinical Course: A Case Report and Review of the Literature |
| title_fullStr | Renal Medullary Carcinoma with an Aggressive Clinical Course: A Case Report and Review of the Literature |
| title_full_unstemmed | Renal Medullary Carcinoma with an Aggressive Clinical Course: A Case Report and Review of the Literature |
| title_short | Renal Medullary Carcinoma with an Aggressive Clinical Course: A Case Report and Review of the Literature |
| title_sort | renal medullary carcinoma with an aggressive clinical course a case report and review of the literature |
| topic | African descent Sickle cell anemia Sickle cell trait Kidney tumor Renal medullary carcinoma Metastasis |
| url | http://www.karger.com/Article/FullText/455007 |
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