Hepatic venous pressure gradient measurement guiding nonselective beta‐blocker therapy in a patient with clinically significant portal hypertension
Abstract Clinically significant portal hypertension (CSPH), defined as a hepatic venous pressure gradient (HVPG) ≥ 10 mmHg, is an independent risk factor for decompensated events in patients with compensated cirrhosis. Currently, the Baveno VII consensus recommends using nonselective beta‐blockers t...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-06-01
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| Series: | Portal Hypertension & Cirrhosis |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/poh2.47 |
| _version_ | 1797791891851313152 |
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| author | Kun Wang Minghui Tian Linpeng Zhang Shanghao Liu Xiaoqing Guo Jianzhong Ma |
| author_facet | Kun Wang Minghui Tian Linpeng Zhang Shanghao Liu Xiaoqing Guo Jianzhong Ma |
| author_sort | Kun Wang |
| collection | DOAJ |
| description | Abstract Clinically significant portal hypertension (CSPH), defined as a hepatic venous pressure gradient (HVPG) ≥ 10 mmHg, is an independent risk factor for decompensated events in patients with compensated cirrhosis. Currently, the Baveno VII consensus recommends using nonselective beta‐blockers to treat compensated cirrhosis in patients with CSPH. Here, we report a unusual case of compensated cirrhosis with CSPH caused by hepatitis B, and we successfully adjust NSBBs drug treatment strategies monitoring by HVPG results and achieve response standards. Timely adjustment of NSBBs drug treatment strategies based on HVPG test results for patients with CSPH can improve the final response rate. |
| first_indexed | 2024-03-13T02:25:17Z |
| format | Article |
| id | doaj.art-9458180e06ba48eb8496e6b9242c979f |
| institution | Directory Open Access Journal |
| issn | 2770-5846 |
| language | English |
| last_indexed | 2024-03-13T02:25:17Z |
| publishDate | 2023-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Portal Hypertension & Cirrhosis |
| spelling | doaj.art-9458180e06ba48eb8496e6b9242c979f2023-06-30T04:46:44ZengWileyPortal Hypertension & Cirrhosis2770-58462023-06-012210510810.1002/poh2.47Hepatic venous pressure gradient measurement guiding nonselective beta‐blocker therapy in a patient with clinically significant portal hypertensionKun Wang0Minghui Tian1Linpeng Zhang2Shanghao Liu3Xiaoqing Guo4Jianzhong Ma5Department of Hepatology Taiyuan Third People's Hospital Taiyuan Shanxi ChinaDepartment of Hepatology Taiyuan Third People's Hospital Taiyuan Shanxi ChinaDepartment of Interventional Taiyuan Third People's Hospital Taiyuan Shanxi ChinaThe First Clinical Medical College of Lanzhou University Lanzhou Gansu ChinaDepartment of Hepatology Taiyuan Third People's Hospital Taiyuan Shanxi ChinaDepartment of Hepatology Taiyuan Third People's Hospital Taiyuan Shanxi ChinaAbstract Clinically significant portal hypertension (CSPH), defined as a hepatic venous pressure gradient (HVPG) ≥ 10 mmHg, is an independent risk factor for decompensated events in patients with compensated cirrhosis. Currently, the Baveno VII consensus recommends using nonselective beta‐blockers to treat compensated cirrhosis in patients with CSPH. Here, we report a unusual case of compensated cirrhosis with CSPH caused by hepatitis B, and we successfully adjust NSBBs drug treatment strategies monitoring by HVPG results and achieve response standards. Timely adjustment of NSBBs drug treatment strategies based on HVPG test results for patients with CSPH can improve the final response rate.https://doi.org/10.1002/poh2.47Hepatic venous pressure gradientNon‐selective beta‐blockerPortal hypertension |
| spellingShingle | Kun Wang Minghui Tian Linpeng Zhang Shanghao Liu Xiaoqing Guo Jianzhong Ma Hepatic venous pressure gradient measurement guiding nonselective beta‐blocker therapy in a patient with clinically significant portal hypertension Portal Hypertension & Cirrhosis Hepatic venous pressure gradient Non‐selective beta‐blocker Portal hypertension |
| title | Hepatic venous pressure gradient measurement guiding nonselective beta‐blocker therapy in a patient with clinically significant portal hypertension |
| title_full | Hepatic venous pressure gradient measurement guiding nonselective beta‐blocker therapy in a patient with clinically significant portal hypertension |
| title_fullStr | Hepatic venous pressure gradient measurement guiding nonselective beta‐blocker therapy in a patient with clinically significant portal hypertension |
| title_full_unstemmed | Hepatic venous pressure gradient measurement guiding nonselective beta‐blocker therapy in a patient with clinically significant portal hypertension |
| title_short | Hepatic venous pressure gradient measurement guiding nonselective beta‐blocker therapy in a patient with clinically significant portal hypertension |
| title_sort | hepatic venous pressure gradient measurement guiding nonselective beta blocker therapy in a patient with clinically significant portal hypertension |
| topic | Hepatic venous pressure gradient Non‐selective beta‐blocker Portal hypertension |
| url | https://doi.org/10.1002/poh2.47 |
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