Technetium-99m in production and use
Several types of generators have been developed for the production of 99mTc. Due to its excellent performances, the chromatographic type, based on the fission-produced 99Mo sorbed in alumina, is predominant. Technetium-99m is obtained in the form of sodium pertechnetate-99mTc. However, due to the kn...
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| Format: | Article |
| Language: | English |
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VINCA Institute of Nuclear Sciences
2009-01-01
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| Series: | Nuclear Technology and Radiation Protection |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/1451-3994/2009/1451-39940901068V.pdf |
| _version_ | 1811251605855535104 |
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| author | Vučina Jurij Nikolić Nadežda Petrović Đokica |
| author_facet | Vučina Jurij Nikolić Nadežda Petrović Đokica |
| author_sort | Vučina Jurij |
| collection | DOAJ |
| description | Several types of generators have been developed for the production of 99mTc. Due to its excellent performances, the chromatographic type, based on the fission-produced 99Mo sorbed in alumina, is predominant. Technetium-99m is obtained in the form of sodium pertechnetate-99mTc. However, due to the known disadvantages of the production of (n, f)99Mo, attempts are made to avoid uranium fission. The technologies based on (n, g)99Mo (sublimation, extraction, gel) are, with the exception of the gel generator, of limited importance. Certain nuclear reactions in cyclotrons can produce 99Mo (or directly 99mTc) but the obtained results are still not satisfying. Technetium-99m is used in the form of radiopharmaceuticals which are prepared by addition of 99mTc-eluate to the inactive components comprised in the 'cold' kits. The chromatographic (n, f)99Mo/99mTc generator and several 99mTc-radiopharmaceuticals have been developed and are regularly produced in the Vinča Institute of Nuclear Sciences (Laboratory for Radioisotopes). |
| first_indexed | 2024-04-12T16:21:57Z |
| format | Article |
| id | doaj.art-945b81e58c9d47d2b88b19de8685cb01 |
| institution | Directory Open Access Journal |
| issn | 1451-3994 |
| language | English |
| last_indexed | 2024-04-12T16:21:57Z |
| publishDate | 2009-01-01 |
| publisher | VINCA Institute of Nuclear Sciences |
| record_format | Article |
| series | Nuclear Technology and Radiation Protection |
| spelling | doaj.art-945b81e58c9d47d2b88b19de8685cb012022-12-22T03:25:31ZengVINCA Institute of Nuclear SciencesNuclear Technology and Radiation Protection1451-39942009-01-01241687310.2298/NTRP0901068VTechnetium-99m in production and useVučina JurijNikolić NadeždaPetrović ĐokicaSeveral types of generators have been developed for the production of 99mTc. Due to its excellent performances, the chromatographic type, based on the fission-produced 99Mo sorbed in alumina, is predominant. Technetium-99m is obtained in the form of sodium pertechnetate-99mTc. However, due to the known disadvantages of the production of (n, f)99Mo, attempts are made to avoid uranium fission. The technologies based on (n, g)99Mo (sublimation, extraction, gel) are, with the exception of the gel generator, of limited importance. Certain nuclear reactions in cyclotrons can produce 99Mo (or directly 99mTc) but the obtained results are still not satisfying. Technetium-99m is used in the form of radiopharmaceuticals which are prepared by addition of 99mTc-eluate to the inactive components comprised in the 'cold' kits. The chromatographic (n, f)99Mo/99mTc generator and several 99mTc-radiopharmaceuticals have been developed and are regularly produced in the Vinča Institute of Nuclear Sciences (Laboratory for Radioisotopes).http://www.doiserbia.nb.rs/img/doi/1451-3994/2009/1451-39940901068V.pdftechnetium-99mmolybdenum-99technetium-99m-generatortechnetium-99m-radiopharmaceuticals |
| spellingShingle | Vučina Jurij Nikolić Nadežda Petrović Đokica Technetium-99m in production and use Nuclear Technology and Radiation Protection technetium-99m molybdenum-99 technetium-99m-generator technetium-99m-radiopharmaceuticals |
| title | Technetium-99m in production and use |
| title_full | Technetium-99m in production and use |
| title_fullStr | Technetium-99m in production and use |
| title_full_unstemmed | Technetium-99m in production and use |
| title_short | Technetium-99m in production and use |
| title_sort | technetium 99m in production and use |
| topic | technetium-99m molybdenum-99 technetium-99m-generator technetium-99m-radiopharmaceuticals |
| url | http://www.doiserbia.nb.rs/img/doi/1451-3994/2009/1451-39940901068V.pdf |
| work_keys_str_mv | AT vucinajurij technetium99minproductionanduse AT nikolicnadezda technetium99minproductionanduse AT petrovicđokica technetium99minproductionanduse |