Secretory IgA in Intestinal Mucosal Secretions as an Adaptive Barrier against Microbial Cells

Secretory IgA in Intestinal Mucosal Secretions as an Adaptive Barrier against Microbial Cells

Secretory IgA (SIgA) is the dominant antibody class in mucosal secretions. The majority of plasma cells producing IgA are located within mucosal membranes lining the intestines. SIgA protects against the adhesion of pathogens and their penetration into the intestinal barrier. Moreover, SIgA regulate...

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Bibliographic Details
Main Authors: Bernadeta Pietrzak, Katarzyna Tomela, Agnieszka Olejnik-Schmidt, Andrzej Mackiewicz, Marcin Schmidt
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
secretory immunoglobulin A
gut
microbiota
immune homeostasis
mucosal secretions
tolerance
Online Access:https://www.mdpi.com/1422-0067/21/23/9254

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