Enhancer prediction in the human genome by probabilistic modelling of the chromatin feature patterns
Abstract Background The binding sites of transcription factors (TFs) and the localisation of histone modifications in the human genome can be quantified by the chromatin immunoprecipitation assay coupled with next-generation sequencing (ChIP-seq). The resulting chromatin feature data has been succes...
Main Authors: | Maria Osmala, Harri Lähdesmäki |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-07-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-020-03621-3 |
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