Differentiation of acute osteoporotic from malignant vertebral compression fractures with conventional MRI and diffusion MR imaging
Aim: To evaluate the role of using a single shot spin echoplanar DW sequence (SSSEP-DWI) compared to conventional MRI and contrast enhanced T1WI in differentiation between vertebral osteoporotic fractures and malignant compression fractures. The sensitivity and specificity of (SSSEP-DWI) will also b...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2017-03-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0378603X16302182 |
| _version_ | 1818281139980206080 |
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| author | Mohamad H. Abowarda Hossam M. Abdel-Rahman Mahmoud M. Taha |
| author_facet | Mohamad H. Abowarda Hossam M. Abdel-Rahman Mahmoud M. Taha |
| author_sort | Mohamad H. Abowarda |
| collection | DOAJ |
| description | Aim: To evaluate the role of using a single shot spin echoplanar DW sequence (SSSEP-DWI) compared to conventional MRI and contrast enhanced T1WI in differentiation between vertebral osteoporotic fractures and malignant compression fractures. The sensitivity and specificity of (SSSEP-DWI) will also be calculated.
Patients and methods: Sixty-eight acute vertebral compression fractures in 41 patients were imaged using conventional MRI, fat suppressed contrast enhanced T1WI and DW sequence on a 1.5 T MR machine. Quantitative assessment of the abnormal signal intensity was done by measuring apparent diffusion coefficients (ADCs). Also, the areas of abnormal signal intensity were compared to adjacent normal marrow.
Results: We had 38 benign fractures, and 30 malignant fractures. Post contrast enhancement showed sensitivity of 92% and specificity of 70% for malignant compression fractures. The hyperintense signal on DWI has 89% PPV for malignancy, while the sensitivity and specificity were 86% and 91% respectively. The mean ADC for malignant fractures was significantly lower than those of osteoporotic fractures (p = 0.0002).
Conclusions: SSSEP-DWI is a reliable adjunct parameter that supports conventional MRI in differentiating benign and malignant vertebral fractures. |
| first_indexed | 2024-12-13T00:00:23Z |
| format | Article |
| id | doaj.art-9460b5f190a641d6961d69cce2123b91 |
| institution | Directory Open Access Journal |
| issn | 0378-603X |
| language | English |
| last_indexed | 2024-12-13T00:00:23Z |
| publishDate | 2017-03-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-9460b5f190a641d6961d69cce2123b912022-12-22T00:06:25ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2017-03-0148120721310.1016/j.ejrnm.2016.11.001Differentiation of acute osteoporotic from malignant vertebral compression fractures with conventional MRI and diffusion MR imagingMohamad H. Abowarda0Hossam M. Abdel-Rahman1Mahmoud M. Taha2Diagnostic Radiology Department, Zagazig University, EgyptDiagnostic Radiology Department, Zagazig University, EgyptDepartment of Neurosurgery, Zagazig University, EgyptAim: To evaluate the role of using a single shot spin echoplanar DW sequence (SSSEP-DWI) compared to conventional MRI and contrast enhanced T1WI in differentiation between vertebral osteoporotic fractures and malignant compression fractures. The sensitivity and specificity of (SSSEP-DWI) will also be calculated. Patients and methods: Sixty-eight acute vertebral compression fractures in 41 patients were imaged using conventional MRI, fat suppressed contrast enhanced T1WI and DW sequence on a 1.5 T MR machine. Quantitative assessment of the abnormal signal intensity was done by measuring apparent diffusion coefficients (ADCs). Also, the areas of abnormal signal intensity were compared to adjacent normal marrow. Results: We had 38 benign fractures, and 30 malignant fractures. Post contrast enhancement showed sensitivity of 92% and specificity of 70% for malignant compression fractures. The hyperintense signal on DWI has 89% PPV for malignancy, while the sensitivity and specificity were 86% and 91% respectively. The mean ADC for malignant fractures was significantly lower than those of osteoporotic fractures (p = 0.0002). Conclusions: SSSEP-DWI is a reliable adjunct parameter that supports conventional MRI in differentiating benign and malignant vertebral fractures.http://www.sciencedirect.com/science/article/pii/S0378603X16302182Osteoporotic malignant fractures DWI |
| spellingShingle | Mohamad H. Abowarda Hossam M. Abdel-Rahman Mahmoud M. Taha Differentiation of acute osteoporotic from malignant vertebral compression fractures with conventional MRI and diffusion MR imaging The Egyptian Journal of Radiology and Nuclear Medicine Osteoporotic malignant fractures DWI |
| title | Differentiation of acute osteoporotic from malignant vertebral compression fractures with conventional MRI and diffusion MR imaging |
| title_full | Differentiation of acute osteoporotic from malignant vertebral compression fractures with conventional MRI and diffusion MR imaging |
| title_fullStr | Differentiation of acute osteoporotic from malignant vertebral compression fractures with conventional MRI and diffusion MR imaging |
| title_full_unstemmed | Differentiation of acute osteoporotic from malignant vertebral compression fractures with conventional MRI and diffusion MR imaging |
| title_short | Differentiation of acute osteoporotic from malignant vertebral compression fractures with conventional MRI and diffusion MR imaging |
| title_sort | differentiation of acute osteoporotic from malignant vertebral compression fractures with conventional mri and diffusion mr imaging |
| topic | Osteoporotic malignant fractures DWI |
| url | http://www.sciencedirect.com/science/article/pii/S0378603X16302182 |
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