Study of Cytotoxic Effect of Aqueous Extract Fenugreek(Trigonella Foenum Graecum L.S) Seeds and The New Complexes of Rh (?) and Pd (?) on Cancer Cell Lines
The effect of the aqueous extract of fenugreek seeds (Trigonella Foenum Graecum L.), Rhodium complex (?) with formula [RhL2CLH2O].1 1/2 ETOH and palladium (?) [pdl2].2ETOH,where L=2-hydroxy phenyl piperonalidine was studied on two cancer cell lines. The first cell line was intestine cancer of female...
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Format: | Article |
Language: | Arabic |
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College of Science for Women, University of Baghdad
2018-12-01
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Series: | Baghdad Science Journal |
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Online Access: | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/3161 |
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author | Baghdad Science Journal |
author_facet | Baghdad Science Journal |
author_sort | Baghdad Science Journal |
collection | DOAJ |
description | The effect of the aqueous extract of fenugreek seeds (Trigonella Foenum Graecum L.), Rhodium complex (?) with formula [RhL2CLH2O].1 1/2 ETOH and palladium (?) [pdl2].2ETOH,where L=2-hydroxy phenyl piperonalidine was studied on two cancer cell lines. The first cell line was intestine cancer of female albino mice (L20B), the second one was Rhabdomysarcomas (RD)cell line in human. The activity of the new complexes and the aqueous extract was compared to the well-known anticancer drug (cis-platin) by utilizing the in vitro system. The cell lines were treated with four concentrations of cis-platin 31.25,62.5,125 and 250 ?g/ml for 72 hour exposure time. The same concentrations were used with extract and the new complexes. This study showed that the aqueous extract, Rhodium (?) and palladium (?) complexes have a promising anticancer cell activity as noticed from their effect on inhibition of the cancer cells . Inhibition rate was increased with concentration for the three treatments and it was found to be significant differences (p |
first_indexed | 2024-12-12T02:32:11Z |
format | Article |
id | doaj.art-9460ed0077f5452386ce312c585725cf |
institution | Directory Open Access Journal |
issn | 2078-8665 2411-7986 |
language | Arabic |
last_indexed | 2024-12-12T02:32:11Z |
publishDate | 2018-12-01 |
publisher | College of Science for Women, University of Baghdad |
record_format | Article |
series | Baghdad Science Journal |
spelling | doaj.art-9460ed0077f5452386ce312c585725cf2022-12-22T00:41:22ZaraCollege of Science for Women, University of BaghdadBaghdad Science Journal2078-86652411-79862018-12-019210.21123/bsj.9.2.289-295Study of Cytotoxic Effect of Aqueous Extract Fenugreek(Trigonella Foenum Graecum L.S) Seeds and The New Complexes of Rh (?) and Pd (?) on Cancer Cell LinesBaghdad Science JournalThe effect of the aqueous extract of fenugreek seeds (Trigonella Foenum Graecum L.), Rhodium complex (?) with formula [RhL2CLH2O].1 1/2 ETOH and palladium (?) [pdl2].2ETOH,where L=2-hydroxy phenyl piperonalidine was studied on two cancer cell lines. The first cell line was intestine cancer of female albino mice (L20B), the second one was Rhabdomysarcomas (RD)cell line in human. The activity of the new complexes and the aqueous extract was compared to the well-known anticancer drug (cis-platin) by utilizing the in vitro system. The cell lines were treated with four concentrations of cis-platin 31.25,62.5,125 and 250 ?g/ml for 72 hour exposure time. The same concentrations were used with extract and the new complexes. This study showed that the aqueous extract, Rhodium (?) and palladium (?) complexes have a promising anticancer cell activity as noticed from their effect on inhibition of the cancer cells . Inhibition rate was increased with concentration for the three treatments and it was found to be significant differences (phttp://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/3161"Fenugreek, rhodium (?) complex, palladium (?) complex" |
spellingShingle | Baghdad Science Journal Study of Cytotoxic Effect of Aqueous Extract Fenugreek(Trigonella Foenum Graecum L.S) Seeds and The New Complexes of Rh (?) and Pd (?) on Cancer Cell Lines Baghdad Science Journal "Fenugreek, rhodium (?) complex, palladium (?) complex" |
title | Study of Cytotoxic Effect of Aqueous Extract Fenugreek(Trigonella Foenum Graecum L.S) Seeds and The New Complexes of Rh (?) and Pd (?) on Cancer Cell Lines |
title_full | Study of Cytotoxic Effect of Aqueous Extract Fenugreek(Trigonella Foenum Graecum L.S) Seeds and The New Complexes of Rh (?) and Pd (?) on Cancer Cell Lines |
title_fullStr | Study of Cytotoxic Effect of Aqueous Extract Fenugreek(Trigonella Foenum Graecum L.S) Seeds and The New Complexes of Rh (?) and Pd (?) on Cancer Cell Lines |
title_full_unstemmed | Study of Cytotoxic Effect of Aqueous Extract Fenugreek(Trigonella Foenum Graecum L.S) Seeds and The New Complexes of Rh (?) and Pd (?) on Cancer Cell Lines |
title_short | Study of Cytotoxic Effect of Aqueous Extract Fenugreek(Trigonella Foenum Graecum L.S) Seeds and The New Complexes of Rh (?) and Pd (?) on Cancer Cell Lines |
title_sort | study of cytotoxic effect of aqueous extract fenugreek trigonella foenum graecum l s seeds and the new complexes of rh and pd on cancer cell lines |
topic | "Fenugreek, rhodium (?) complex, palladium (?) complex" |
url | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/3161 |
work_keys_str_mv | AT baghdadsciencejournal studyofcytotoxiceffectofaqueousextractfenugreektrigonellafoenumgraecumlsseedsandthenewcomplexesofrhandpdoncancercelllines |