Efficacy and safety of Gyejibokryeong-hwan (GBH) in major depressive disorder: study protocol for multicentre randomised controlled trial

Efficacy and safety of Gyejibokryeong-hwan (GBH) in major depressive disorder: study protocol for multicentre randomised controlled trial

Abstract Background Gyejibokryeong-hwan (GBH) is an herbal medicine composed of five herbs. It has been widely used to treat gynaecological diseases in traditional East Asian medicine. Recent animal studies suggest antidepressant effects of GBH. In this trial, we explore the efficacy and safety of G...

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Bibliographic Details
Main Authors: Yujin Choi, In Chul Jung, Ju Yeon Kim, Seung-Hun Cho, Yunna Kim, Sun-Yong Chung, Hui-Yong Kwak, Doo Suk Lee, Wonwoo Lee, In-Jeong Nam, Changsop Yang, Mi Young Lee
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Trials
Subjects:
Major depressive disorder
Phase II study
Gyejibokryeong-hwan
Guizhifuling-wan
Keishibukuryo-Gan
Herbal medicine
Online Access:https://doi.org/10.1186/s13063-022-06339-0

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