Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA
HK022 put is an RNA element that inhibits transcription termination without aids from protein factors. Here, authors solved cryo-EM structures of put-associated RNA polymerase and showed the structure of putRNA and its binding to the RNA polymerase.
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-32315-y |
| _version_ | 1811340364597952512 |
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| author | Seungha Hwang Paul Dominic B. Olinares Jimin Lee Jinwoo Kim Brian T. Chait Rodney A. King Jin Young Kang |
| author_facet | Seungha Hwang Paul Dominic B. Olinares Jimin Lee Jinwoo Kim Brian T. Chait Rodney A. King Jin Young Kang |
| author_sort | Seungha Hwang |
| collection | DOAJ |
| description | HK022 put is an RNA element that inhibits transcription termination without aids from protein factors. Here, authors solved cryo-EM structures of put-associated RNA polymerase and showed the structure of putRNA and its binding to the RNA polymerase. |
| first_indexed | 2024-04-13T18:40:57Z |
| format | Article |
| id | doaj.art-9464cb87d69e4715979d97c940859e73 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-13T18:40:57Z |
| publishDate | 2022-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-9464cb87d69e4715979d97c940859e732022-12-22T02:34:44ZengNature PortfolioNature Communications2041-17232022-08-0113111410.1038/s41467-022-32315-yStructural basis of transcriptional regulation by a nascent RNA element, HK022 putRNASeungha Hwang0Paul Dominic B. Olinares1Jimin Lee2Jinwoo Kim3Brian T. Chait4Rodney A. King5Jin Young Kang6Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST)Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller UniversityDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST)Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST)Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller UniversityBiology Department, Western Kentucky UniversityDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST)HK022 put is an RNA element that inhibits transcription termination without aids from protein factors. Here, authors solved cryo-EM structures of put-associated RNA polymerase and showed the structure of putRNA and its binding to the RNA polymerase.https://doi.org/10.1038/s41467-022-32315-y |
| spellingShingle | Seungha Hwang Paul Dominic B. Olinares Jimin Lee Jinwoo Kim Brian T. Chait Rodney A. King Jin Young Kang Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA Nature Communications |
| title | Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA |
| title_full | Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA |
| title_fullStr | Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA |
| title_full_unstemmed | Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA |
| title_short | Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA |
| title_sort | structural basis of transcriptional regulation by a nascent rna element hk022 putrna |
| url | https://doi.org/10.1038/s41467-022-32315-y |
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