Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors

Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors

Neural progenitors in the embryonic neocortex must be tightly regulated in order to generate the correct number and projection neuron subtypes necessary for the formation of functional neocortical circuits. In this study, we show that the intracellular protein Suppressor of Fused (Sufu) regulates th...

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Bibliographic Details
Main Authors: Odessa R. Yabut, Hui Xuan Ng, Gloria Fernandez, Keejung Yoon, Jeremy Kuhn, Samuel J. Pleasure
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Journal of Developmental Biology
Subjects:
Suppressor of Fused
Sonic Hedgehog
Gli3
corticogenesis
neurogenesis
Online Access:http://www.mdpi.com/2221-3759/4/4/29

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