Pharmacological screening of plants recommended by folk medicine as anti-snake venom: I. Analgesic and anti-inflammatory activities
We have observed that several plants used popularly as anti-snake venom show anti-inflammatory activity. From the list prepared by Rizzini, Mors and Pereira some species have been selected and tested for analgesic activity (number of contortions) and anti-inflammatory activity (Evans blue dye diffus...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Fundação Oswaldo Cruz (FIOCRUZ)
1991-01-01
|
| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000600046 |
| _version_ | 1797758516480442368 |
|---|---|
| author | Bettina M. Ruppelt Edna F. R. Pereira Lilia C. Gonçalves Nuno A. Pereira |
| author_facet | Bettina M. Ruppelt Edna F. R. Pereira Lilia C. Gonçalves Nuno A. Pereira |
| author_sort | Bettina M. Ruppelt |
| collection | DOAJ |
| description | We have observed that several plants used popularly as anti-snake venom show anti-inflammatory activity. From the list prepared by Rizzini, Mors and Pereira some species have been selected and tested for analgesic activity (number of contortions) and anti-inflammatory activity (Evans blue dye diffusion - 1% solution) according to Whittle's technique (intraperitoneal administration of 0.1 N-acetic acid 0.1 ml/10 g) in mice. Previous oral administration of a 10% infusion (dry plant) or 20% (fresh plant) corresponding to 1 or 2 g/Kg of Apuleia leiocarpa, Casearia sylvestris, Brunfelsia uniflora, Chiococca brachiata, Cynara scolymus, Dorstenia brasiliensis, Elephantopus scaber, Marsypianthes chamaedrys, Mikania glomerata and Trianosperma tayuya demonstrated analgesic and/or anti-inflammatory activities of varied intensity |
| first_indexed | 2024-03-12T18:31:09Z |
| format | Article |
| id | doaj.art-9466e247e01e4f1995ad59922f2f1b45 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:31:09Z |
| publishDate | 1991-01-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-9466e247e01e4f1995ad59922f2f1b452023-08-02T08:19:12ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80601991-01-018620320510.1590/S0074-02761991000600046Pharmacological screening of plants recommended by folk medicine as anti-snake venom: I. Analgesic and anti-inflammatory activitiesBettina M. RuppeltEdna F. R. PereiraLilia C. GonçalvesNuno A. PereiraWe have observed that several plants used popularly as anti-snake venom show anti-inflammatory activity. From the list prepared by Rizzini, Mors and Pereira some species have been selected and tested for analgesic activity (number of contortions) and anti-inflammatory activity (Evans blue dye diffusion - 1% solution) according to Whittle's technique (intraperitoneal administration of 0.1 N-acetic acid 0.1 ml/10 g) in mice. Previous oral administration of a 10% infusion (dry plant) or 20% (fresh plant) corresponding to 1 or 2 g/Kg of Apuleia leiocarpa, Casearia sylvestris, Brunfelsia uniflora, Chiococca brachiata, Cynara scolymus, Dorstenia brasiliensis, Elephantopus scaber, Marsypianthes chamaedrys, Mikania glomerata and Trianosperma tayuya demonstrated analgesic and/or anti-inflammatory activities of varied intensityhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000600046anti-snake plantsanalgesic and anti-inflamatory activityfolkloric uses |
| spellingShingle | Bettina M. Ruppelt Edna F. R. Pereira Lilia C. Gonçalves Nuno A. Pereira Pharmacological screening of plants recommended by folk medicine as anti-snake venom: I. Analgesic and anti-inflammatory activities Memorias do Instituto Oswaldo Cruz anti-snake plants analgesic and anti-inflamatory activity folkloric uses |
| title | Pharmacological screening of plants recommended by folk medicine as anti-snake venom: I. Analgesic and anti-inflammatory activities |
| title_full | Pharmacological screening of plants recommended by folk medicine as anti-snake venom: I. Analgesic and anti-inflammatory activities |
| title_fullStr | Pharmacological screening of plants recommended by folk medicine as anti-snake venom: I. Analgesic and anti-inflammatory activities |
| title_full_unstemmed | Pharmacological screening of plants recommended by folk medicine as anti-snake venom: I. Analgesic and anti-inflammatory activities |
| title_short | Pharmacological screening of plants recommended by folk medicine as anti-snake venom: I. Analgesic and anti-inflammatory activities |
| title_sort | pharmacological screening of plants recommended by folk medicine as anti snake venom i analgesic and anti inflammatory activities |
| topic | anti-snake plants analgesic and anti-inflamatory activity folkloric uses |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000600046 |
| work_keys_str_mv | AT bettinamruppelt pharmacologicalscreeningofplantsrecommendedbyfolkmedicineasantisnakevenomianalgesicandantiinflammatoryactivities AT ednafrpereira pharmacologicalscreeningofplantsrecommendedbyfolkmedicineasantisnakevenomianalgesicandantiinflammatoryactivities AT liliacgoncalves pharmacologicalscreeningofplantsrecommendedbyfolkmedicineasantisnakevenomianalgesicandantiinflammatoryactivities AT nunoapereira pharmacologicalscreeningofplantsrecommendedbyfolkmedicineasantisnakevenomianalgesicandantiinflammatoryactivities |