How to choose an appropriate drug dosage form for the treatment of respiratory infections in children: Facts and tips

The treatment of respiratory infections in children requires special attention, since the paediatric population has rather specific characteristics and consists of heterogenous subgroups. In this context, the choice of a suitable drug dosage form is of particular importance, depending on the active...

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Main Authors: Cvijić Sandra, Mirković Dušica, Krajišnik Danina
Format: Article
Language:srp
Published: Pharmaceutical Association of Serbia, Belgrade, Serbia 2022-01-01
Series:Arhiv za farmaciju
Subjects:
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2022/0004-19632203353C.pdf
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author Cvijić Sandra
Mirković Dušica
Krajišnik Danina
author_facet Cvijić Sandra
Mirković Dušica
Krajišnik Danina
author_sort Cvijić Sandra
collection DOAJ
description The treatment of respiratory infections in children requires special attention, since the paediatric population has rather specific characteristics and consists of heterogenous subgroups. In this context, the choice of a suitable drug dosage form is of particular importance, depending on the active substance properties, along with the age and general condition of a paediatric patient. The most commonly used pharmaceutical products for respiratory infections in children include oral, parenteral and inhalation dosage forms, although a large number of drugs are not available in a suitable dosage form and/or strength for paediatric age, leading to the frequent use of unauthorized drugs (i.e., unlicensed use). Other important issues that should be considered when choosing the appropriate paediatric dosage form and/or compounding procedure are related to the careful considerations of the pharmaceutical product composition (safety of excipients) and the choice of administration/dosing device in relation to a child's age. This paper provides an overview of paediatric dosage forms used in the treatment of respiratory infections in children, their benefits and limitations. The review includes examples of various pharmaceutical products, along with the considerations regarding administration/dosing devices. Specific characteristics of paediatric populations affecting the decision on the choice of age-appropriate paediatric formulation are also addressed.
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spelling doaj.art-94685e141a1b4ede93ddcd3507fbfe532022-12-22T03:04:19ZsrpPharmaceutical Association of Serbia, Belgrade, SerbiaArhiv za farmaciju0004-19632217-87672022-01-0172335337210.5937/arhfarm72-376430004-19632203353CHow to choose an appropriate drug dosage form for the treatment of respiratory infections in children: Facts and tipsCvijić Sandra0https://orcid.org/0000-0001-8291-791XMirković Dušica1Krajišnik Danina2https://orcid.org/0000-0002-5525-0109University of Belgrade, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, SerbiaMilitary Medical Academy, Institute of Pharmacy, Belgrade, SerbiaUniversity of Belgrade, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, SerbiaThe treatment of respiratory infections in children requires special attention, since the paediatric population has rather specific characteristics and consists of heterogenous subgroups. In this context, the choice of a suitable drug dosage form is of particular importance, depending on the active substance properties, along with the age and general condition of a paediatric patient. The most commonly used pharmaceutical products for respiratory infections in children include oral, parenteral and inhalation dosage forms, although a large number of drugs are not available in a suitable dosage form and/or strength for paediatric age, leading to the frequent use of unauthorized drugs (i.e., unlicensed use). Other important issues that should be considered when choosing the appropriate paediatric dosage form and/or compounding procedure are related to the careful considerations of the pharmaceutical product composition (safety of excipients) and the choice of administration/dosing device in relation to a child's age. This paper provides an overview of paediatric dosage forms used in the treatment of respiratory infections in children, their benefits and limitations. The review includes examples of various pharmaceutical products, along with the considerations regarding administration/dosing devices. Specific characteristics of paediatric populations affecting the decision on the choice of age-appropriate paediatric formulation are also addressed.https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2022/0004-19632203353C.pdfpaediatric dosage formsage-appropriate formulationextemporaneous compoundingadministration/dosing devicesrespiratory infections
spellingShingle Cvijić Sandra
Mirković Dušica
Krajišnik Danina
How to choose an appropriate drug dosage form for the treatment of respiratory infections in children: Facts and tips
Arhiv za farmaciju
paediatric dosage forms
age-appropriate formulation
extemporaneous compounding
administration/dosing devices
respiratory infections
title How to choose an appropriate drug dosage form for the treatment of respiratory infections in children: Facts and tips
title_full How to choose an appropriate drug dosage form for the treatment of respiratory infections in children: Facts and tips
title_fullStr How to choose an appropriate drug dosage form for the treatment of respiratory infections in children: Facts and tips
title_full_unstemmed How to choose an appropriate drug dosage form for the treatment of respiratory infections in children: Facts and tips
title_short How to choose an appropriate drug dosage form for the treatment of respiratory infections in children: Facts and tips
title_sort how to choose an appropriate drug dosage form for the treatment of respiratory infections in children facts and tips
topic paediatric dosage forms
age-appropriate formulation
extemporaneous compounding
administration/dosing devices
respiratory infections
url https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2022/0004-19632203353C.pdf
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