An uncommon presentation of a rare disease: A case of anti-glomerular basement membrane disease without renal involvement

Anti-glomerular basement membrane disease (anti-GBM) is a well-documented, small vessel vasculitis that is classically associated with glomerulonephritis and alveolitis [1]. However, regardless of clinical process, not every patient will present with a constellation of classically associated symptom...

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Main Authors: Jeremy Polman, Rory Panzarello, Pratik Patel, Vasudev Tati
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Respiratory Medicine Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213007120304962
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author Jeremy Polman
Rory Panzarello
Pratik Patel
Vasudev Tati
author_facet Jeremy Polman
Rory Panzarello
Pratik Patel
Vasudev Tati
author_sort Jeremy Polman
collection DOAJ
description Anti-glomerular basement membrane disease (anti-GBM) is a well-documented, small vessel vasculitis that is classically associated with glomerulonephritis and alveolitis [1]. However, regardless of clinical process, not every patient will present with a constellation of classically associated symptoms. Literature review demonstrates that early anti-GBM disease can present as glomerulonephritis without alveolitis [2,3]. In this case report, we describe the unique clinical course of a 26-year-old male who originally presented with hemoptysis and his subsequent clinical workup revealing anti-glomerular basement membrane disease without renal involvement.
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spelling doaj.art-946a370cfe474845adc81b290c48c6082022-12-21T19:44:26ZengElsevierRespiratory Medicine Case Reports2213-00712020-01-0131101282An uncommon presentation of a rare disease: A case of anti-glomerular basement membrane disease without renal involvementJeremy Polman0Rory Panzarello1Pratik Patel2Vasudev Tati3Corresponding author.; Baton Rouge General Internal Medicine Residency Program, USABaton Rouge General Internal Medicine Residency Program, USABaton Rouge General Internal Medicine Residency Program, USABaton Rouge General Internal Medicine Residency Program, USAAnti-glomerular basement membrane disease (anti-GBM) is a well-documented, small vessel vasculitis that is classically associated with glomerulonephritis and alveolitis [1]. However, regardless of clinical process, not every patient will present with a constellation of classically associated symptoms. Literature review demonstrates that early anti-GBM disease can present as glomerulonephritis without alveolitis [2,3]. In this case report, we describe the unique clinical course of a 26-year-old male who originally presented with hemoptysis and his subsequent clinical workup revealing anti-glomerular basement membrane disease without renal involvement.http://www.sciencedirect.com/science/article/pii/S2213007120304962Goodpasture's diseaseDiffuse alveolar hemorrhageRare presentation
spellingShingle Jeremy Polman
Rory Panzarello
Pratik Patel
Vasudev Tati
An uncommon presentation of a rare disease: A case of anti-glomerular basement membrane disease without renal involvement
Respiratory Medicine Case Reports
Goodpasture's disease
Diffuse alveolar hemorrhage
Rare presentation
title An uncommon presentation of a rare disease: A case of anti-glomerular basement membrane disease without renal involvement
title_full An uncommon presentation of a rare disease: A case of anti-glomerular basement membrane disease without renal involvement
title_fullStr An uncommon presentation of a rare disease: A case of anti-glomerular basement membrane disease without renal involvement
title_full_unstemmed An uncommon presentation of a rare disease: A case of anti-glomerular basement membrane disease without renal involvement
title_short An uncommon presentation of a rare disease: A case of anti-glomerular basement membrane disease without renal involvement
title_sort uncommon presentation of a rare disease a case of anti glomerular basement membrane disease without renal involvement
topic Goodpasture's disease
Diffuse alveolar hemorrhage
Rare presentation
url http://www.sciencedirect.com/science/article/pii/S2213007120304962
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