Application of Enzymes in Regioselective and Stereoselective Organic Reactions
Nowadays, biocatalysts have received much more attention in chemistry regarding their potential to enable high efficiency, high yield, and eco-friendly processes for a myriad of applications. Nature’s vast repository of catalysts has inspired synthetic chemists. Furthermore, the revolutionary techno...
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MDPI AG
2020-07-01
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Online Access: | https://www.mdpi.com/2073-4344/10/8/832 |
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author | Ruipu Mu Zhaoshuai Wang Max C. Wamsley Colbee N. Duke Payton H. Lii Sarah E. Epley London C. Todd Patty J. Roberts |
author_facet | Ruipu Mu Zhaoshuai Wang Max C. Wamsley Colbee N. Duke Payton H. Lii Sarah E. Epley London C. Todd Patty J. Roberts |
author_sort | Ruipu Mu |
collection | DOAJ |
description | Nowadays, biocatalysts have received much more attention in chemistry regarding their potential to enable high efficiency, high yield, and eco-friendly processes for a myriad of applications. Nature’s vast repository of catalysts has inspired synthetic chemists. Furthermore, the revolutionary technologies in bioengineering have provided the fast discovery and evolution of enzymes that empower chemical synthesis. This article attempts to deliver a comprehensive overview of the last two decades of investigation into enzymatic reactions and highlights the effective performance progress of bio-enzymes exploited in organic synthesis. Based on the types of enzymatic reactions and enzyme commission (E.C.) numbers, the enzymes discussed in the article are classified into oxidoreductases, transferases, hydrolases, and lyases. These applications should provide us with some insight into enzyme design strategies and molecular mechanisms. |
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format | Article |
id | doaj.art-946b4ab261cc484caee6e58b982ec612 |
institution | Directory Open Access Journal |
issn | 2073-4344 |
language | English |
last_indexed | 2024-03-10T18:15:09Z |
publishDate | 2020-07-01 |
publisher | MDPI AG |
record_format | Article |
series | Catalysts |
spelling | doaj.art-946b4ab261cc484caee6e58b982ec6122023-11-20T07:47:34ZengMDPI AGCatalysts2073-43442020-07-0110883210.3390/catal10080832Application of Enzymes in Regioselective and Stereoselective Organic ReactionsRuipu Mu0Zhaoshuai Wang1Max C. Wamsley2Colbee N. Duke3Payton H. Lii4Sarah E. Epley5London C. Todd6Patty J. Roberts7Department of Chemistry, Centenary College of Louisiana, Shreveport, LA 71104, USADepartment of Pharmaceutical Science, College of Pharmacy, University of Kentucky, Lexington, KY 40536, USADepartment of Chemistry, Centenary College of Louisiana, Shreveport, LA 71104, USADepartment of Chemistry, Centenary College of Louisiana, Shreveport, LA 71104, USADepartment of Chemistry, Centenary College of Louisiana, Shreveport, LA 71104, USADepartment of Chemistry, Centenary College of Louisiana, Shreveport, LA 71104, USADepartment of Chemistry, Centenary College of Louisiana, Shreveport, LA 71104, USADepartment of Chemistry, Centenary College of Louisiana, Shreveport, LA 71104, USANowadays, biocatalysts have received much more attention in chemistry regarding their potential to enable high efficiency, high yield, and eco-friendly processes for a myriad of applications. Nature’s vast repository of catalysts has inspired synthetic chemists. Furthermore, the revolutionary technologies in bioengineering have provided the fast discovery and evolution of enzymes that empower chemical synthesis. This article attempts to deliver a comprehensive overview of the last two decades of investigation into enzymatic reactions and highlights the effective performance progress of bio-enzymes exploited in organic synthesis. Based on the types of enzymatic reactions and enzyme commission (E.C.) numbers, the enzymes discussed in the article are classified into oxidoreductases, transferases, hydrolases, and lyases. These applications should provide us with some insight into enzyme design strategies and molecular mechanisms.https://www.mdpi.com/2073-4344/10/8/832regioselectivitystereoselectivitybiocatalystenzymatic reactionsprotein engineering |
spellingShingle | Ruipu Mu Zhaoshuai Wang Max C. Wamsley Colbee N. Duke Payton H. Lii Sarah E. Epley London C. Todd Patty J. Roberts Application of Enzymes in Regioselective and Stereoselective Organic Reactions Catalysts regioselectivity stereoselectivity biocatalyst enzymatic reactions protein engineering |
title | Application of Enzymes in Regioselective and Stereoselective Organic Reactions |
title_full | Application of Enzymes in Regioselective and Stereoselective Organic Reactions |
title_fullStr | Application of Enzymes in Regioselective and Stereoselective Organic Reactions |
title_full_unstemmed | Application of Enzymes in Regioselective and Stereoselective Organic Reactions |
title_short | Application of Enzymes in Regioselective and Stereoselective Organic Reactions |
title_sort | application of enzymes in regioselective and stereoselective organic reactions |
topic | regioselectivity stereoselectivity biocatalyst enzymatic reactions protein engineering |
url | https://www.mdpi.com/2073-4344/10/8/832 |
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