Crystal structure of Drosophila Piwi
PIWI-clade Argonautes bind PIWI-interacting RNAs (piRNAs) to silence transposons and maintain genome integrity in animal gonads. Here the authors present the crystal structure of a Drosophila Piwi–piRNA complex isolated from cultured fly ovarian somatic cells and find that it contains a non-canonica...
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Bibliographic Details
| Main Authors: |
Sonomi Yamaguchi,
Akira Oe,
Kazumichi M. Nishida,
Keitaro Yamashita,
Asako Kajiya,
Seiichi Hirano,
Naoki Matsumoto,
Naoshi Dohmae,
Ryuichiro Ishitani,
Kuniaki Saito,
Haruhiko Siomi,
Hiroshi Nishimasu,
Mikiko C. Siomi,
Osamu Nureki |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2020-02-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-14687-1
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