Sex, sex chromosomes and gene expression

<p>Abstract</p> <p>The X chromosome has fewer testis-specific genes than autosomes in many species. This bias is commonly attributed to X inactivation in spermatogenesis but a recent paper in <it>BMC Biology </it>provides evidence against X inactivation in <it>Dro...

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Bibliographic Details
Main Authors: Wu Chung-I, Lu Xuemei
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/9/30
Description
Summary:<p>Abstract</p> <p>The X chromosome has fewer testis-specific genes than autosomes in many species. This bias is commonly attributed to X inactivation in spermatogenesis but a recent paper in <it>BMC Biology </it>provides evidence against X inactivation in <it>Drosophila </it>and proposes that somatic tissue- and testis- but not ovary-specific genes tend not to be located on the X chromosome. Here, we discuss possible mechanisms underlying this bias, including sexual antagonism and dosage compensation.</p> <p>See research article {<url>http://www.biomedcentral.com/1741-7007/9/29</url>}</p>
ISSN:1741-7007