Lantus, the first peakless basal insulin analogue: 10 years of clinical experience in children and adolescents
This review analyses existing literature, including authors' own data, describing the results of clinical trials which assess safety and efficacy of insulin Glargine (Lantus?) in children and adolescents, as well as peculiar features of T1D management in this age group, including the challenge...
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2014-07-01
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| Series: | Сахарный диабет |
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| Online Access: | https://www.dia-endojournals.ru/jour/article/view/6581 |
| _version_ | 1797255223786340352 |
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| author | Tamara Leonidovna Kuraeva |
| author_facet | Tamara Leonidovna Kuraeva |
| author_sort | Tamara Leonidovna Kuraeva |
| collection | DOAJ |
| description | This review analyses existing literature, including authors' own data, describing the results of clinical trials which assess safety and efficacy of insulin Glargine (Lantus?) in children and adolescents, as well as peculiar features of T1D management in this age group, including the challenge of reducing the rate of hypoglycemia while maintaining adequate glycemic control. The article also discusses various issues in T1D management in children and adolescents, including the role of glycemic control in development of vascular complications, hypoglycemia and the variability of glycemia. The data confirm the high efficacy of Lantus insulin in respect to metabolic control, including the decrease in the incidence of hypoglycemia and in variability of glycemic profile, the safety of its clinical use in treatment of children, including young children, and adolescents, as well as its ability to improve the quality of life for patients and their parents. |
| first_indexed | 2024-03-08T15:20:22Z |
| format | Article |
| id | doaj.art-947bfb4adf1b459f8c9e536232bf74b8 |
| institution | Directory Open Access Journal |
| issn | 2072-0351 2072-0378 |
| language | English |
| last_indexed | 2024-04-24T22:02:26Z |
| publishDate | 2014-07-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj.art-947bfb4adf1b459f8c9e536232bf74b82024-03-20T11:47:59ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782014-07-0117210511510.14341/DM20142105-1156440Lantus, the first peakless basal insulin analogue: 10 years of clinical experience in children and adolescentsTamara Leonidovna Kuraeva0Endocrinology Research Centre, MoscowThis review analyses existing literature, including authors' own data, describing the results of clinical trials which assess safety and efficacy of insulin Glargine (Lantus?) in children and adolescents, as well as peculiar features of T1D management in this age group, including the challenge of reducing the rate of hypoglycemia while maintaining adequate glycemic control. The article also discusses various issues in T1D management in children and adolescents, including the role of glycemic control in development of vascular complications, hypoglycemia and the variability of glycemia. The data confirm the high efficacy of Lantus insulin in respect to metabolic control, including the decrease in the incidence of hypoglycemia and in variability of glycemic profile, the safety of its clinical use in treatment of children, including young children, and adolescents, as well as its ability to improve the quality of life for patients and their parents.https://www.dia-endojournals.ru/jour/article/view/6581t1dchildren and adolescentsinsulin glargineglycemic controlsafety |
| spellingShingle | Tamara Leonidovna Kuraeva Lantus, the first peakless basal insulin analogue: 10 years of clinical experience in children and adolescents Сахарный диабет t1d children and adolescents insulin glargine glycemic control safety |
| title | Lantus, the first peakless basal insulin analogue: 10 years of clinical experience in children and adolescents |
| title_full | Lantus, the first peakless basal insulin analogue: 10 years of clinical experience in children and adolescents |
| title_fullStr | Lantus, the first peakless basal insulin analogue: 10 years of clinical experience in children and adolescents |
| title_full_unstemmed | Lantus, the first peakless basal insulin analogue: 10 years of clinical experience in children and adolescents |
| title_short | Lantus, the first peakless basal insulin analogue: 10 years of clinical experience in children and adolescents |
| title_sort | lantus the first peakless basal insulin analogue 10 years of clinical experience in children and adolescents |
| topic | t1d children and adolescents insulin glargine glycemic control safety |
| url | https://www.dia-endojournals.ru/jour/article/view/6581 |
| work_keys_str_mv | AT tamaraleonidovnakuraeva lantusthefirstpeaklessbasalinsulinanalogue10yearsofclinicalexperienceinchildrenandadolescents |