Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore
Engineered biological nanopores enable observation of single molecule chemistry events; however a cylindrical pore geometry can have undesired effects. The authors report a conical biological pore which was embedded with tetrachloroaurate(III) to allow for discrimination between different biothiols.
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-13677-2 |
| _version_ | 1818342642892668928 |
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| author | Jiao Cao Wendong Jia Jinyue Zhang Xiumei Xu Shuanghong Yan Yuqin Wang Panke Zhang Hong-Yuan Chen Shuo Huang |
| author_facet | Jiao Cao Wendong Jia Jinyue Zhang Xiumei Xu Shuanghong Yan Yuqin Wang Panke Zhang Hong-Yuan Chen Shuo Huang |
| author_sort | Jiao Cao |
| collection | DOAJ |
| description | Engineered biological nanopores enable observation of single molecule chemistry events; however a cylindrical pore geometry can have undesired effects. The authors report a conical biological pore which was embedded with tetrachloroaurate(III) to allow for discrimination between different biothiols. |
| first_indexed | 2024-12-13T16:17:56Z |
| format | Article |
| id | doaj.art-94823f338928445084725edff4f78e3a |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-13T16:17:56Z |
| publishDate | 2019-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-94823f338928445084725edff4f78e3a2022-12-21T23:38:47ZengNature PortfolioNature Communications2041-17232019-12-0110111110.1038/s41467-019-13677-2Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanoporeJiao Cao0Wendong Jia1Jinyue Zhang2Xiumei Xu3Shuanghong Yan4Yuqin Wang5Panke Zhang6Hong-Yuan Chen7Shuo Huang8State Key Laboratory of Analytical Chemistry for Life Sciences, Nanjing UniversityState Key Laboratory of Analytical Chemistry for Life Sciences, Nanjing UniversityState Key Laboratory of Analytical Chemistry for Life Sciences, Nanjing UniversityState Key Laboratory of Analytical Chemistry for Life Sciences, Nanjing UniversityState Key Laboratory of Analytical Chemistry for Life Sciences, Nanjing UniversityState Key Laboratory of Analytical Chemistry for Life Sciences, Nanjing UniversityState Key Laboratory of Analytical Chemistry for Life Sciences, Nanjing UniversityState Key Laboratory of Analytical Chemistry for Life Sciences, Nanjing UniversityState Key Laboratory of Analytical Chemistry for Life Sciences, Nanjing UniversityEngineered biological nanopores enable observation of single molecule chemistry events; however a cylindrical pore geometry can have undesired effects. The authors report a conical biological pore which was embedded with tetrachloroaurate(III) to allow for discrimination between different biothiols.https://doi.org/10.1038/s41467-019-13677-2 |
| spellingShingle | Jiao Cao Wendong Jia Jinyue Zhang Xiumei Xu Shuanghong Yan Yuqin Wang Panke Zhang Hong-Yuan Chen Shuo Huang Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore Nature Communications |
| title | Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore |
| title_full | Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore |
| title_fullStr | Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore |
| title_full_unstemmed | Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore |
| title_short | Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore |
| title_sort | giant single molecule chemistry events observed from a tetrachloroaurate iii embedded mycobacterium smegmatis porin a nanopore |
| url | https://doi.org/10.1038/s41467-019-13677-2 |
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