Long non-coding RNA H19 enhances the pro-apoptotic activity of ITF2357 (a histone deacetylase inhibitor) in colorectal cancer cells

Long non-coding RNA H19 enhances the pro-apoptotic activity of ITF2357 (a histone deacetylase inhibitor) in colorectal cancer cells

Introduction: Long non-coding RNA H19 (lncH19) is highly expressed in colorectal cancer (CRC) and plays critical roles in tumor development, proliferation, metastasis, and drug resistance. Indeed, the expression of lncH19 usually affects the outcomes of chemo-, endocrine, and targeted therapies. ITF...

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Bibliographic Details
Main Authors: Chiara Zichittella, Marco Loria, Adriana Celesia, Diana Di Liberto, Chiara Corrado, Riccardo Alessandro, Sonia Emanuele, Alice Conigliaro
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Pharmacology
Subjects:
lncH19
colorectal cancer
histone deacetylase inhibitor
apoptosis
drug resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1275833/full

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