Adenoviral vectored vaccination protects against Crimean-Congo Haemorrhagic Fever disease in a lethal challenge modelResearch in context

Adenoviral vectored vaccination protects against Crimean-Congo Haemorrhagic Fever disease in a lethal challenge modelResearch in context

Summary: Background: The tick-borne bunyavirus, Crimean-Congo Haemorrhagic Fever virus (CCHFV), can cause severe febrile illness in humans and has a wide geographic range that continues to expand due to tick migration. Currently, there are no licensed vaccines against CCHFV for widespread usage. Me...

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Bibliographic Details
Main Authors: Jack E. Saunders, Ciaran Gilbride, Stuart Dowall, Susan Morris, Marta Ulaszewska, Alexandra J. Spencer, Emma Rayner, Victoria A. Graham, Emma Kennedy, Kelly Thomas, Roger Hewson, Sarah C. Gilbert, Sandra Belij-Rammerstorfer, Teresa Lambe
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:EBioMedicine
Subjects:
Vaccine
CCHFV
Heterologous immunisation
ChAdOx2
Antibodies
T cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423000889

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