Effects of Pre-Donated Autologous Blood Transfusion on Peri-Operative Hemoglobin Concentration and Mid-Term Health Outcomes in Primary Total Knee Arthroplasty
The effects of auto-BT in primary TKA on the perioperative hemoglobin (Hb) concentration and mid-term health outcomes are unknown. This study was performed to analyze the detailed changes in the perioperative Hb concentration before and after the operation (days 0–14 postoperatively), cardiovascular...
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MDPI AG
2022-04-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/8/2252 |
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| author | Jun Tomura Daichi Morikawa Masahiko Nozawa Muneaki Ishijima Sung-Gon Kim |
| author_facet | Jun Tomura Daichi Morikawa Masahiko Nozawa Muneaki Ishijima Sung-Gon Kim |
| author_sort | Jun Tomura |
| collection | DOAJ |
| description | The effects of auto-BT in primary TKA on the perioperative hemoglobin (Hb) concentration and mid-term health outcomes are unknown. This study was performed to analyze the detailed changes in the perioperative Hb concentration before and after the operation (days 0–14 postoperatively), cardiovascular events, and mortality rate within 1 and 5 years postoperatively. One hundred patients undergoing primary TKA with auto-BT using 800 mL of preoperatively collected blood at the authors’ institution were included. The mean Hb concentration before and after autologous blood collection was 12.7 ± 1.1 and 11.7 ± 1.2 g/dL, respectively. After primary TKA with auto-BT, the mean Hb concentration on day 0, 1, 3, 7, and 14 was 10.2 ± 1.2, 9.9 ± 1.2, 10.4 ± 1.3, 10.5 ± 1.3, and 11.0 ± 1.3 g/dL, respectively. Only one (1%) patient required additional allogenic blood transfusion. No patients developed cardiovascular events, and the 1- and 5-year postoperative mortality rate was 1.0% and 2.0%, respectively. Primary TKA with auto-BT showed relatively small perioperative changes in the Hb concentration, a low incidence of cardiovascular events, and a low mortality rate within 1 and 5 years postoperatively. These findings suggest that auto-BT, in which blood is preoperatively collected, is beneficial for patient safety and health, even if its cost-effectiveness may be debatable. |
| first_indexed | 2024-03-09T10:33:15Z |
| format | Article |
| id | doaj.art-94832d252f1f4e2b8b2de48c2df462f1 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T10:33:15Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-94832d252f1f4e2b8b2de48c2df462f12023-12-01T21:07:18ZengMDPI AGJournal of Clinical Medicine2077-03832022-04-01118225210.3390/jcm11082252Effects of Pre-Donated Autologous Blood Transfusion on Peri-Operative Hemoglobin Concentration and Mid-Term Health Outcomes in Primary Total Knee ArthroplastyJun Tomura0Daichi Morikawa1Masahiko Nozawa2Muneaki Ishijima3Sung-Gon Kim4Department of Orthopaedic Surgery, Juntendo University Nerima Hospital, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-0033, JapanDepartment of Orthopaedic Surgery, Juntendo University Nerima Hospital, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-0033, JapanDepartment of Orthopaedic Surgery, Juntendo University Nerima Hospital, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-0033, JapanDepartment of Orthopaedics, Faculty of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-0033, JapanDepartment of Orthopaedic Surgery, Juntendo University Nerima Hospital, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-0033, JapanThe effects of auto-BT in primary TKA on the perioperative hemoglobin (Hb) concentration and mid-term health outcomes are unknown. This study was performed to analyze the detailed changes in the perioperative Hb concentration before and after the operation (days 0–14 postoperatively), cardiovascular events, and mortality rate within 1 and 5 years postoperatively. One hundred patients undergoing primary TKA with auto-BT using 800 mL of preoperatively collected blood at the authors’ institution were included. The mean Hb concentration before and after autologous blood collection was 12.7 ± 1.1 and 11.7 ± 1.2 g/dL, respectively. After primary TKA with auto-BT, the mean Hb concentration on day 0, 1, 3, 7, and 14 was 10.2 ± 1.2, 9.9 ± 1.2, 10.4 ± 1.3, 10.5 ± 1.3, and 11.0 ± 1.3 g/dL, respectively. Only one (1%) patient required additional allogenic blood transfusion. No patients developed cardiovascular events, and the 1- and 5-year postoperative mortality rate was 1.0% and 2.0%, respectively. Primary TKA with auto-BT showed relatively small perioperative changes in the Hb concentration, a low incidence of cardiovascular events, and a low mortality rate within 1 and 5 years postoperatively. These findings suggest that auto-BT, in which blood is preoperatively collected, is beneficial for patient safety and health, even if its cost-effectiveness may be debatable.https://www.mdpi.com/2077-0383/11/8/2252autologous blood transfusiontotal knee arthroplastyblood lossmortalitycardiovascular event |
| spellingShingle | Jun Tomura Daichi Morikawa Masahiko Nozawa Muneaki Ishijima Sung-Gon Kim Effects of Pre-Donated Autologous Blood Transfusion on Peri-Operative Hemoglobin Concentration and Mid-Term Health Outcomes in Primary Total Knee Arthroplasty Journal of Clinical Medicine autologous blood transfusion total knee arthroplasty blood loss mortality cardiovascular event |
| title | Effects of Pre-Donated Autologous Blood Transfusion on Peri-Operative Hemoglobin Concentration and Mid-Term Health Outcomes in Primary Total Knee Arthroplasty |
| title_full | Effects of Pre-Donated Autologous Blood Transfusion on Peri-Operative Hemoglobin Concentration and Mid-Term Health Outcomes in Primary Total Knee Arthroplasty |
| title_fullStr | Effects of Pre-Donated Autologous Blood Transfusion on Peri-Operative Hemoglobin Concentration and Mid-Term Health Outcomes in Primary Total Knee Arthroplasty |
| title_full_unstemmed | Effects of Pre-Donated Autologous Blood Transfusion on Peri-Operative Hemoglobin Concentration and Mid-Term Health Outcomes in Primary Total Knee Arthroplasty |
| title_short | Effects of Pre-Donated Autologous Blood Transfusion on Peri-Operative Hemoglobin Concentration and Mid-Term Health Outcomes in Primary Total Knee Arthroplasty |
| title_sort | effects of pre donated autologous blood transfusion on peri operative hemoglobin concentration and mid term health outcomes in primary total knee arthroplasty |
| topic | autologous blood transfusion total knee arthroplasty blood loss mortality cardiovascular event |
| url | https://www.mdpi.com/2077-0383/11/8/2252 |
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