Progress in pathogenesis of Guillain⁃Barré syndrome
Guillain ⁃ Barré syndrome (GBS) is an acute inflammatory disorder of the peripheral nervous system and consists of at least four subtypes of acute peripheral neuropathy namely, acute inflammatroy demyelinating polyneuropathy, acute motor axonal neuropathy, acute motor and sensory axonal neuropathy,...
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| Format: | Article |
| Language: | English |
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Tianjin Huanhu Hospital
2012-04-01
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| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
| Subjects: | |
| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/133 |
| _version_ | 1818057595545452544 |
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| author | Jing ZHANG Li GUO |
| author_facet | Jing ZHANG Li GUO |
| author_sort | Jing ZHANG |
| collection | DOAJ |
| description | Guillain ⁃ Barré syndrome (GBS) is an acute inflammatory disorder of the peripheral nervous system and consists of at least four subtypes of acute peripheral neuropathy namely, acute inflammatroy demyelinating polyneuropathy, acute motor axonal neuropathy, acute motor and sensory axonal neuropathy, and Miller ⁃ Fisher syndrome. Major advances have been made in the understanding of the mechanism of some subtypes. GBS is thought to be due to autoimmunity for which immunotherapy is usually prescribed. About 20% patients died or had persistent disability despite normative immunotherapy. More research is needed to identify better treatment regimens and new therapeutic strategies. In this review, we summarized the epidemiology, diagnosis, pathogenesis, and treatment of the principal subtypes.
DOI：10.3969/j.issn.1672⁃6731.2012.02.004 |
| first_indexed | 2024-12-10T12:47:14Z |
| format | Article |
| id | doaj.art-9483c0841698406997be5bdd9402c8fa |
| institution | Directory Open Access Journal |
| issn | 1672-6731 |
| language | English |
| last_indexed | 2024-12-10T12:47:14Z |
| publishDate | 2012-04-01 |
| publisher | Tianjin Huanhu Hospital |
| record_format | Article |
| series | Chinese Journal of Contemporary Neurology and Neurosurgery |
| spelling | doaj.art-9483c0841698406997be5bdd9402c8fa2022-12-22T01:48:23ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312012-04-01122117121132Progress in pathogenesis of Guillain⁃Barré syndromeJing ZHANGLi GUOGuillain ⁃ Barré syndrome (GBS) is an acute inflammatory disorder of the peripheral nervous system and consists of at least four subtypes of acute peripheral neuropathy namely, acute inflammatroy demyelinating polyneuropathy, acute motor axonal neuropathy, acute motor and sensory axonal neuropathy, and Miller ⁃ Fisher syndrome. Major advances have been made in the understanding of the mechanism of some subtypes. GBS is thought to be due to autoimmunity for which immunotherapy is usually prescribed. About 20% patients died or had persistent disability despite normative immunotherapy. More research is needed to identify better treatment regimens and new therapeutic strategies. In this review, we summarized the epidemiology, diagnosis, pathogenesis, and treatment of the principal subtypes. DOI：10.3969/j.issn.1672⁃6731.2012.02.004http://www.cjcnn.org/index.php/cjcnn/article/view/133Guillain⁃Barré syndromeReview |
| spellingShingle | Jing ZHANG Li GUO Progress in pathogenesis of Guillain⁃Barré syndrome Chinese Journal of Contemporary Neurology and Neurosurgery Guillain⁃Barré syndrome Review |
| title | Progress in pathogenesis of Guillain⁃Barré syndrome |
| title_full | Progress in pathogenesis of Guillain⁃Barré syndrome |
| title_fullStr | Progress in pathogenesis of Guillain⁃Barré syndrome |
| title_full_unstemmed | Progress in pathogenesis of Guillain⁃Barré syndrome |
| title_short | Progress in pathogenesis of Guillain⁃Barré syndrome |
| title_sort | progress in pathogenesis of guillain⁃barre syndrome |
| topic | Guillain⁃Barré syndrome Review |
| url | http://www.cjcnn.org/index.php/cjcnn/article/view/133 |
| work_keys_str_mv | AT jingzhang progressinpathogenesisofguillainbarresyndrome AT liguo progressinpathogenesisofguillainbarresyndrome |