Simvastatin Efficiently Reduces Levels of Alzheimer’s Amyloid Beta in Yeast

Simvastatin Efficiently Reduces Levels of Alzheimer’s Amyloid Beta in Yeast

A large-scale epidemiology study on statins previously showed that simvastatin was unique among statins in reducing the incidence of dementia. Since amyloid beta (Aβ42) is the protein that is most associated with Alzheimer’s disease, this study has focused on how simvastatin influ...

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Bibliographic Details
Main Authors: Sudip Dhakal, Mishal Subhan, Joshua M. Fraser, Kenneth Gardiner, Ian Macreadie
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
amyloid beta
ageing
autophagy
proteostasis
statins
yeast
Online Access:https://www.mdpi.com/1422-0067/20/14/3531

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