Cerebral Small Vessel Disease
Cerebral small vessel disease (CSVD) is composed of several diseases affecting the small arteries, arterioles, venules, and capillaries of the brain, and refers to several pathological processes and etiologies. Neuroimaging features of CSVD include recent small subcortical infarcts, lacunes, white m...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2018-12-01
|
| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.1177/0963689718795148 |
| _version_ | 1818313821795647488 |
|---|---|
| author | Qian Li Yang Yang Cesar Reis Tao Tao Wanwei Li Xiaogang Li John H. Zhang |
| author_facet | Qian Li Yang Yang Cesar Reis Tao Tao Wanwei Li Xiaogang Li John H. Zhang |
| author_sort | Qian Li |
| collection | DOAJ |
| description | Cerebral small vessel disease (CSVD) is composed of several diseases affecting the small arteries, arterioles, venules, and capillaries of the brain, and refers to several pathological processes and etiologies. Neuroimaging features of CSVD include recent small subcortical infarcts, lacunes, white matter hyperintensities, perivascular spaces, microbleeds, and brain atrophy. The main clinical manifestations of CSVD include stroke, cognitive decline, dementia, psychiatric disorders, abnormal gait, and urinary incontinence. Currently, there are no specific preventive or therapeutic measures to improve this condition. In this review, we will discuss the pathophysiology, clinical aspects, neuroimaging, progress of research to treat and prevent CSVD and current treatment of this disease. |
| first_indexed | 2024-12-13T08:39:50Z |
| format | Article |
| id | doaj.art-94860bf06edc43cd8ab56f1c759f4a1e |
| institution | Directory Open Access Journal |
| issn | 0963-6897 1555-3892 |
| language | English |
| last_indexed | 2024-12-13T08:39:50Z |
| publishDate | 2018-12-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Cell Transplantation |
| spelling | doaj.art-94860bf06edc43cd8ab56f1c759f4a1e2022-12-21T23:53:34ZengSAGE PublishingCell Transplantation0963-68971555-38922018-12-012710.1177/0963689718795148Cerebral Small Vessel DiseaseQian Li0Yang Yang1Cesar Reis2Tao Tao3Wanwei Li4Xiaogang Li5John H. Zhang6 Both the authors contributed equally as co-authors. Both the authors contributed equally as co-authors. Department of Physiology and Pharmacology, Loma Linda University School of Medicine, Loma Linda, CA, USA Department of Neurology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China Department of Pediatrics, The Third Affiliated Hospital & Field Surgery Institution, Army Medical University, Chongqing, China Department of Neurology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China Department of Anesthesiology, Loma Linda University School of Medicine, Loma Linda, CA, USACerebral small vessel disease (CSVD) is composed of several diseases affecting the small arteries, arterioles, venules, and capillaries of the brain, and refers to several pathological processes and etiologies. Neuroimaging features of CSVD include recent small subcortical infarcts, lacunes, white matter hyperintensities, perivascular spaces, microbleeds, and brain atrophy. The main clinical manifestations of CSVD include stroke, cognitive decline, dementia, psychiatric disorders, abnormal gait, and urinary incontinence. Currently, there are no specific preventive or therapeutic measures to improve this condition. In this review, we will discuss the pathophysiology, clinical aspects, neuroimaging, progress of research to treat and prevent CSVD and current treatment of this disease.https://doi.org/10.1177/0963689718795148 |
| spellingShingle | Qian Li Yang Yang Cesar Reis Tao Tao Wanwei Li Xiaogang Li John H. Zhang Cerebral Small Vessel Disease Cell Transplantation |
| title | Cerebral Small Vessel Disease |
| title_full | Cerebral Small Vessel Disease |
| title_fullStr | Cerebral Small Vessel Disease |
| title_full_unstemmed | Cerebral Small Vessel Disease |
| title_short | Cerebral Small Vessel Disease |
| title_sort | cerebral small vessel disease |
| url | https://doi.org/10.1177/0963689718795148 |
| work_keys_str_mv | AT qianli cerebralsmallvesseldisease AT yangyang cerebralsmallvesseldisease AT cesarreis cerebralsmallvesseldisease AT taotao cerebralsmallvesseldisease AT wanweili cerebralsmallvesseldisease AT xiaogangli cerebralsmallvesseldisease AT johnhzhang cerebralsmallvesseldisease |