Could nanotechnology improve exercise performance? Evidence from animal studies
Abstract This review provides the current state of knowledge regarding the use of nutritional nanocompounds on exercise performance. The reviewed studies used the following nanocompounds: resveratrol-loaded lipid nanoparticles, folic acid into layered hydroxide nanoparticle, redox-active nanoparticl...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Associação Brasileira de Divulgação Científica
2024-04-01
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| Series: | Brazilian Journal of Medical and Biological Research |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2024000100301&lng=en&tlng=en |
| _version_ | 1797194744189681664 |
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| author | M.R. Lima B.J. Moreira R. Bertuzzi A.E. Lima-Silva |
| author_facet | M.R. Lima B.J. Moreira R. Bertuzzi A.E. Lima-Silva |
| author_sort | M.R. Lima |
| collection | DOAJ |
| description | Abstract This review provides the current state of knowledge regarding the use of nutritional nanocompounds on exercise performance. The reviewed studies used the following nanocompounds: resveratrol-loaded lipid nanoparticles, folic acid into layered hydroxide nanoparticle, redox-active nanoparticles with nitroxide radicals, and iron into liposomes. Most of these nutritional nanocompounds seem to improve performance in endurance exercise compared to the active compound in the non-nanoencapsulated form and/or placebo. Nutritional nanocompounds also induced the following physiological and metabolic alterations: 1) improved antioxidant activity and reduced oxidative stress; 2) reduction in inflammation status; 3) maintenance of muscle integrity; 4) improvement in mitochondrial function and quality; 5) enhanced glucose levels during exercise; 6) higher muscle and hepatic glycogen levels; and 7) increased serum and liver iron content. However, all the reviewed studies were conducted in animals (mice and rats). In conclusion, nutritional nanocompounds are a promising approach to improving exercise performance. As the studies using nutritional nanocompounds were all conducted in animals, further studies in humans are necessary to better understand the application of nutritional nanocompounds in sport and exercise science. |
| first_indexed | 2024-04-24T06:01:09Z |
| format | Article |
| id | doaj.art-9486ddc2f98d4beaa1ee0b165745d1e8 |
| institution | Directory Open Access Journal |
| issn | 1414-431X |
| language | English |
| last_indexed | 2024-04-24T06:01:09Z |
| publishDate | 2024-04-01 |
| publisher | Associação Brasileira de Divulgação Científica |
| record_format | Article |
| series | Brazilian Journal of Medical and Biological Research |
| spelling | doaj.art-9486ddc2f98d4beaa1ee0b165745d1e82024-04-23T07:37:26ZengAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological Research1414-431X2024-04-015710.1590/1414-431x2024e13360Could nanotechnology improve exercise performance? Evidence from animal studiesM.R. Limahttps://orcid.org/0009-0009-2522-7774B.J. Moreirahttps://orcid.org/0000-0002-0811-7735R. Bertuzzihttps://orcid.org/0000-0002-0407-9620A.E. Lima-Silvahttps://orcid.org/0000-0002-0613-5104Abstract This review provides the current state of knowledge regarding the use of nutritional nanocompounds on exercise performance. The reviewed studies used the following nanocompounds: resveratrol-loaded lipid nanoparticles, folic acid into layered hydroxide nanoparticle, redox-active nanoparticles with nitroxide radicals, and iron into liposomes. Most of these nutritional nanocompounds seem to improve performance in endurance exercise compared to the active compound in the non-nanoencapsulated form and/or placebo. Nutritional nanocompounds also induced the following physiological and metabolic alterations: 1) improved antioxidant activity and reduced oxidative stress; 2) reduction in inflammation status; 3) maintenance of muscle integrity; 4) improvement in mitochondrial function and quality; 5) enhanced glucose levels during exercise; 6) higher muscle and hepatic glycogen levels; and 7) increased serum and liver iron content. However, all the reviewed studies were conducted in animals (mice and rats). In conclusion, nutritional nanocompounds are a promising approach to improving exercise performance. As the studies using nutritional nanocompounds were all conducted in animals, further studies in humans are necessary to better understand the application of nutritional nanocompounds in sport and exercise science.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2024000100301&lng=en&tlng=enNanotechnologyExercise performanceSport nutritionMetabolism |
| spellingShingle | M.R. Lima B.J. Moreira R. Bertuzzi A.E. Lima-Silva Could nanotechnology improve exercise performance? Evidence from animal studies Brazilian Journal of Medical and Biological Research Nanotechnology Exercise performance Sport nutrition Metabolism |
| title | Could nanotechnology improve exercise performance? Evidence from animal studies |
| title_full | Could nanotechnology improve exercise performance? Evidence from animal studies |
| title_fullStr | Could nanotechnology improve exercise performance? Evidence from animal studies |
| title_full_unstemmed | Could nanotechnology improve exercise performance? Evidence from animal studies |
| title_short | Could nanotechnology improve exercise performance? Evidence from animal studies |
| title_sort | could nanotechnology improve exercise performance evidence from animal studies |
| topic | Nanotechnology Exercise performance Sport nutrition Metabolism |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2024000100301&lng=en&tlng=en |
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