Quantitative Determination of Bisphenol A and Its Congeners in Plant-Based Beverages by Liquid Chromatography Coupled to Tandem Mass Spectrometry
The consumption of plant-based beverages as an alternative to cow’s milk has recently gained vast attention worldwide. The aim of this work is to monitor the intake of Bisphenol A (BPA), Bisphenol B (BPB) and Bisphenol S (BPS) in the Italian population through the consumption of these foodstuffs. Sp...
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| Format: | Article |
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MDPI AG
2022-11-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/11/23/3853 |
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| author | Marica Erminia Schiano Federica Sodano Chiara Cassiano Ferdinando Fiorino Serenella Seccia Maria Grazia Rimoli Stefania Albrizio |
| author_facet | Marica Erminia Schiano Federica Sodano Chiara Cassiano Ferdinando Fiorino Serenella Seccia Maria Grazia Rimoli Stefania Albrizio |
| author_sort | Marica Erminia Schiano |
| collection | DOAJ |
| description | The consumption of plant-based beverages as an alternative to cow’s milk has recently gained vast attention worldwide. The aim of this work is to monitor the intake of Bisphenol A (BPA), Bisphenol B (BPB) and Bisphenol S (BPS) in the Italian population through the consumption of these foodstuffs. Specifically, the development and validation of an analytical procedure for the quantitative determination of the analytes by liquid chromatography coupled to tandem mass spectrometry was reported. Thirty-four samples of plant-based beverages (soya, coconut, almond, oats and rice) of popular brands marketed in Italy were analyzed. BPA was found in 32% of the samples, while BPB was found in 3% of the samples. The risk assessment using the Rapid Assessment of Contaminant Exposure (RACE) tool demonstrated that there was no risk for all population groups, when using the current Tolerable Daily Intake (TDI) of 4 ng/kg body weight (bw)/day as a toxicological reference point. In contrast, using the new temporary TDI of 0.04 ng/kg bw/day, the existing risk was found to be real for all population groups. If this value were to become final, even more attention would have to be paid to the possible presence of BPA in food to protect consumer health. |
| first_indexed | 2024-03-09T17:47:37Z |
| format | Article |
| id | doaj.art-9487a323d46b4ea0bc3845e1ad2c522f |
| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-03-09T17:47:37Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-9487a323d46b4ea0bc3845e1ad2c522f2023-11-24T10:59:40ZengMDPI AGFoods2304-81582022-11-011123385310.3390/foods11233853Quantitative Determination of Bisphenol A and Its Congeners in Plant-Based Beverages by Liquid Chromatography Coupled to Tandem Mass SpectrometryMarica Erminia Schiano0Federica Sodano1Chiara Cassiano2Ferdinando Fiorino3Serenella Seccia4Maria Grazia Rimoli5Stefania Albrizio6Department of Pharmacy, University of Naples Federico II, 80131 Naples, ItalyDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, ItalyDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, ItalyDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, ItalyDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, ItalyDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, ItalyDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, ItalyThe consumption of plant-based beverages as an alternative to cow’s milk has recently gained vast attention worldwide. The aim of this work is to monitor the intake of Bisphenol A (BPA), Bisphenol B (BPB) and Bisphenol S (BPS) in the Italian population through the consumption of these foodstuffs. Specifically, the development and validation of an analytical procedure for the quantitative determination of the analytes by liquid chromatography coupled to tandem mass spectrometry was reported. Thirty-four samples of plant-based beverages (soya, coconut, almond, oats and rice) of popular brands marketed in Italy were analyzed. BPA was found in 32% of the samples, while BPB was found in 3% of the samples. The risk assessment using the Rapid Assessment of Contaminant Exposure (RACE) tool demonstrated that there was no risk for all population groups, when using the current Tolerable Daily Intake (TDI) of 4 ng/kg body weight (bw)/day as a toxicological reference point. In contrast, using the new temporary TDI of 0.04 ng/kg bw/day, the existing risk was found to be real for all population groups. If this value were to become final, even more attention would have to be paid to the possible presence of BPA in food to protect consumer health.https://www.mdpi.com/2304-8158/11/23/3853bisphenolsliquid chromatography with tandem mass spectrometry (LC-MS/MS)plant-based beveragessolid-phase extractionrisk assessment |
| spellingShingle | Marica Erminia Schiano Federica Sodano Chiara Cassiano Ferdinando Fiorino Serenella Seccia Maria Grazia Rimoli Stefania Albrizio Quantitative Determination of Bisphenol A and Its Congeners in Plant-Based Beverages by Liquid Chromatography Coupled to Tandem Mass Spectrometry Foods bisphenols liquid chromatography with tandem mass spectrometry (LC-MS/MS) plant-based beverages solid-phase extraction risk assessment |
| title | Quantitative Determination of Bisphenol A and Its Congeners in Plant-Based Beverages by Liquid Chromatography Coupled to Tandem Mass Spectrometry |
| title_full | Quantitative Determination of Bisphenol A and Its Congeners in Plant-Based Beverages by Liquid Chromatography Coupled to Tandem Mass Spectrometry |
| title_fullStr | Quantitative Determination of Bisphenol A and Its Congeners in Plant-Based Beverages by Liquid Chromatography Coupled to Tandem Mass Spectrometry |
| title_full_unstemmed | Quantitative Determination of Bisphenol A and Its Congeners in Plant-Based Beverages by Liquid Chromatography Coupled to Tandem Mass Spectrometry |
| title_short | Quantitative Determination of Bisphenol A and Its Congeners in Plant-Based Beverages by Liquid Chromatography Coupled to Tandem Mass Spectrometry |
| title_sort | quantitative determination of bisphenol a and its congeners in plant based beverages by liquid chromatography coupled to tandem mass spectrometry |
| topic | bisphenols liquid chromatography with tandem mass spectrometry (LC-MS/MS) plant-based beverages solid-phase extraction risk assessment |
| url | https://www.mdpi.com/2304-8158/11/23/3853 |
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