Use of Natural Products in Leishmaniasis Chemotherapy: An Overview
Leishmaniasis is an infectious parasitic disease that is caused by protozoa of the genus Leishmania, a member of the Trypanosomatidae family. Leishmaniasis is classified by the World Health Organization as a neglected tropical disease that is responsible for millions of deaths worldwide. Although th...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-11-01
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| Series: | Frontiers in Chemistry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2020.579891/full |
| _version_ | 1819158991870099456 |
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| author | Luiza F. O. Gervazoni Gabrielle B. Barcellos Taiana Ferreira-Paes Elmo E. Almeida-Amaral |
| author_facet | Luiza F. O. Gervazoni Gabrielle B. Barcellos Taiana Ferreira-Paes Elmo E. Almeida-Amaral |
| author_sort | Luiza F. O. Gervazoni |
| collection | DOAJ |
| description | Leishmaniasis is an infectious parasitic disease that is caused by protozoa of the genus Leishmania, a member of the Trypanosomatidae family. Leishmaniasis is classified by the World Health Organization as a neglected tropical disease that is responsible for millions of deaths worldwide. Although there are many possible treatments for leishmaniasis, these treatments remain mostly ineffective, expensive, and long treatment, as well as causing side effects and leading to the development of resistance. For novel and effective treatments to combat leishmaniasis, many research groups have sought to utilize natural products. In addition to exhibiting potential as therapeutic compounds, natural products may also contribute to the development of new drugs based on their chemical structures. This review presents the most promising natural products, including crude extracts and isolated compounds, employed against Leishmania spp. |
| first_indexed | 2024-12-22T16:33:27Z |
| format | Article |
| id | doaj.art-9487ce439eed4ad1bafa4a50d7ca095e |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-12-22T16:33:27Z |
| publishDate | 2020-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-9487ce439eed4ad1bafa4a50d7ca095e2022-12-21T18:20:01ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462020-11-01810.3389/fchem.2020.579891579891Use of Natural Products in Leishmaniasis Chemotherapy: An OverviewLuiza F. O. GervazoniGabrielle B. BarcellosTaiana Ferreira-PaesElmo E. Almeida-AmaralLeishmaniasis is an infectious parasitic disease that is caused by protozoa of the genus Leishmania, a member of the Trypanosomatidae family. Leishmaniasis is classified by the World Health Organization as a neglected tropical disease that is responsible for millions of deaths worldwide. Although there are many possible treatments for leishmaniasis, these treatments remain mostly ineffective, expensive, and long treatment, as well as causing side effects and leading to the development of resistance. For novel and effective treatments to combat leishmaniasis, many research groups have sought to utilize natural products. In addition to exhibiting potential as therapeutic compounds, natural products may also contribute to the development of new drugs based on their chemical structures. This review presents the most promising natural products, including crude extracts and isolated compounds, employed against Leishmania spp.https://www.frontiersin.org/articles/10.3389/fchem.2020.579891/fullnatural productLeishmaniasischemotherapyin vivoin vitrointracellular amastigotes |
| spellingShingle | Luiza F. O. Gervazoni Gabrielle B. Barcellos Taiana Ferreira-Paes Elmo E. Almeida-Amaral Use of Natural Products in Leishmaniasis Chemotherapy: An Overview Frontiers in Chemistry natural product Leishmaniasis chemotherapy in vivo in vitro intracellular amastigotes |
| title | Use of Natural Products in Leishmaniasis Chemotherapy: An Overview |
| title_full | Use of Natural Products in Leishmaniasis Chemotherapy: An Overview |
| title_fullStr | Use of Natural Products in Leishmaniasis Chemotherapy: An Overview |
| title_full_unstemmed | Use of Natural Products in Leishmaniasis Chemotherapy: An Overview |
| title_short | Use of Natural Products in Leishmaniasis Chemotherapy: An Overview |
| title_sort | use of natural products in leishmaniasis chemotherapy an overview |
| topic | natural product Leishmaniasis chemotherapy in vivo in vitro intracellular amastigotes |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2020.579891/full |
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