cGAS/STING and innate brain inflammation following acute high-fat feeding

cGAS/STING and innate brain inflammation following acute high-fat feeding

Obesity, prediabetes, and diabetes are growing in prevalence worldwide. These metabolic disorders are associated with neurodegenerative diseases, particularly Alzheimer’s disease and Alzheimer’s disease related dementias. Innate inflammatory signaling plays a critical role in this association, poten...

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Bibliographic Details
Main Authors: Sarah E. Elzinga, Rosemary Henn, Benjamin J. Murdock, Bhumsoo Kim, John M. Hayes, Faye Mendelson, Ian Webber-Davis, Sam Teener, Crystal Pacut, Stephen I. Lentz, Eva L. Feldman
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
cGAS/STING
acute
innate inflammation
microglia
high fat diet
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1012594/full

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