EXPERIENCE OF USING DEXMEDETOMIDINE FOR DRUG SEDATION IN INTRALUMINAL ENDOSCOPIC SURGERY
Goal of the study: to evaluate the possibility of using dexmedetomidine for drug sedation when performing intraluminal endoscopic surgery (ILES). Materials and methods. 136 cases of dexmedetomidine used were analyzed in 100 patients at the age of 58.0 ± 1.5 years old (Me = 59, Min = 22, Max = 87) du...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
New Terra Publishing House
2018-01-01
|
| Series: | Вестник анестезиологии и реаниматологии |
| Subjects: | |
| Online Access: | https://www.vair-journal.com/jour/article/view/128 |
| _version_ | 1797697694728192000 |
|---|---|
| author | M. G. Kovalev I. V. Shlyk Yu. S. Polushin A. L. Akopov A. A. Smirnov A. A. Rusanov |
| author_facet | M. G. Kovalev I. V. Shlyk Yu. S. Polushin A. L. Akopov A. A. Smirnov A. A. Rusanov |
| author_sort | M. G. Kovalev |
| collection | DOAJ |
| description | Goal of the study: to evaluate the possibility of using dexmedetomidine for drug sedation when performing intraluminal endoscopic surgery (ILES). Materials and methods. 136 cases of dexmedetomidine used were analyzed in 100 patients at the age of 58.0 ± 1.5 years old (Me = 59, Min = 22, Max = 87) during the first and repeated video-assisted bronchoscopies, esophagogastroscopies, duodenoscopies and colonoscopies lasting for 73 ± 3 min. (Me = 65, Min = 15, Max = 330). Results. Sole use of dexmedetomidine was effective only in short-term ILES causing minimal trauma. If ILES lasts longer and causes bigger trauma dexmedetomidine is to be combined with nefopam, fentanyl, trimeperidin, propofol, and ketamine. Combined use of dexmedetomidine resulted in the reduction of doses of the drugs, provided opportunity to manage the depth of sedation without depression of spontaneous respiration, post-operative and post-procedure agitation, algidity, nausea and vomit. Conclusion. Dexmedetomidine can be considered as the drug of choice for sedation in ILES. |
| first_indexed | 2024-03-12T03:43:44Z |
| format | Article |
| id | doaj.art-948a711f19284391a5ce18db40972629 |
| institution | Directory Open Access Journal |
| issn | 2078-5658 2541-8653 |
| language | Russian |
| last_indexed | 2024-03-12T03:43:44Z |
| publishDate | 2018-01-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Вестник анестезиологии и реаниматологии |
| spelling | doaj.art-948a711f19284391a5ce18db409726292023-09-03T13:02:12ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532018-01-01136404710.21292/2078-5658-2016-13-6-40-47128EXPERIENCE OF USING DEXMEDETOMIDINE FOR DRUG SEDATION IN INTRALUMINAL ENDOSCOPIC SURGERYM. G. Kovalev0I. V. Shlyk1Yu. S. Polushin2A. L. Akopov3A. A. Smirnov4A. A. Rusanov5ФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И. П. Павлова» МЗ РФ, Санкт-ПетербургФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И. П. Павлова» МЗ РФ, Санкт-ПетербургФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И. П. Павлова» МЗ РФ, Санкт-ПетербургФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И. П. Павлова» МЗ РФ, Санкт-ПетербургФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И. П. Павлова» МЗ РФ, Санкт-ПетербургФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И. П. Павлова» МЗ РФ, Санкт-ПетербургGoal of the study: to evaluate the possibility of using dexmedetomidine for drug sedation when performing intraluminal endoscopic surgery (ILES). Materials and methods. 136 cases of dexmedetomidine used were analyzed in 100 patients at the age of 58.0 ± 1.5 years old (Me = 59, Min = 22, Max = 87) during the first and repeated video-assisted bronchoscopies, esophagogastroscopies, duodenoscopies and colonoscopies lasting for 73 ± 3 min. (Me = 65, Min = 15, Max = 330). Results. Sole use of dexmedetomidine was effective only in short-term ILES causing minimal trauma. If ILES lasts longer and causes bigger trauma dexmedetomidine is to be combined with nefopam, fentanyl, trimeperidin, propofol, and ketamine. Combined use of dexmedetomidine resulted in the reduction of doses of the drugs, provided opportunity to manage the depth of sedation without depression of spontaneous respiration, post-operative and post-procedure agitation, algidity, nausea and vomit. Conclusion. Dexmedetomidine can be considered as the drug of choice for sedation in ILES.https://www.vair-journal.com/jour/article/view/128дексмедетомидинмедикаментозная седациявнутрипросветные эндоскопические вмешательства |
| spellingShingle | M. G. Kovalev I. V. Shlyk Yu. S. Polushin A. L. Akopov A. A. Smirnov A. A. Rusanov EXPERIENCE OF USING DEXMEDETOMIDINE FOR DRUG SEDATION IN INTRALUMINAL ENDOSCOPIC SURGERY Вестник анестезиологии и реаниматологии дексмедетомидин медикаментозная седация внутрипросветные эндоскопические вмешательства |
| title | EXPERIENCE OF USING DEXMEDETOMIDINE FOR DRUG SEDATION IN INTRALUMINAL ENDOSCOPIC SURGERY |
| title_full | EXPERIENCE OF USING DEXMEDETOMIDINE FOR DRUG SEDATION IN INTRALUMINAL ENDOSCOPIC SURGERY |
| title_fullStr | EXPERIENCE OF USING DEXMEDETOMIDINE FOR DRUG SEDATION IN INTRALUMINAL ENDOSCOPIC SURGERY |
| title_full_unstemmed | EXPERIENCE OF USING DEXMEDETOMIDINE FOR DRUG SEDATION IN INTRALUMINAL ENDOSCOPIC SURGERY |
| title_short | EXPERIENCE OF USING DEXMEDETOMIDINE FOR DRUG SEDATION IN INTRALUMINAL ENDOSCOPIC SURGERY |
| title_sort | experience of using dexmedetomidine for drug sedation in intraluminal endoscopic surgery |
| topic | дексмедетомидин медикаментозная седация внутрипросветные эндоскопические вмешательства |
| url | https://www.vair-journal.com/jour/article/view/128 |
| work_keys_str_mv | AT mgkovalev experienceofusingdexmedetomidinefordrugsedationinintraluminalendoscopicsurgery AT ivshlyk experienceofusingdexmedetomidinefordrugsedationinintraluminalendoscopicsurgery AT yuspolushin experienceofusingdexmedetomidinefordrugsedationinintraluminalendoscopicsurgery AT alakopov experienceofusingdexmedetomidinefordrugsedationinintraluminalendoscopicsurgery AT aasmirnov experienceofusingdexmedetomidinefordrugsedationinintraluminalendoscopicsurgery AT aarusanov experienceofusingdexmedetomidinefordrugsedationinintraluminalendoscopicsurgery |