ATRIAL FIBRILLATION AND FLUTTER IN HYPERTROPHIC CARDIOMYOPATHY
Aim. To find out the factors associated with atrial fibrillation/flutter (AF) in patients with hypertrophiccardiomyopathy.Material and methods. Totally 182 HCMP patients included, of those 103 — men (mean age 59,6±14,6y). Diagnosis of AFwas set using ECG or Holter monitoring of ECG using medical cha...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«FIRMA «SILICEA» LLC
2015-05-01
|
| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/316 |
| _version_ | 1826561378162311168 |
|---|---|
| author | N. S. Krylova A. E. Demkina F. M. Khashieva E. A. Kovalevskaya N. G. Poteshkina |
| author_facet | N. S. Krylova A. E. Demkina F. M. Khashieva E. A. Kovalevskaya N. G. Poteshkina |
| author_sort | N. S. Krylova |
| collection | DOAJ |
| description | Aim. To find out the factors associated with atrial fibrillation/flutter (AF) in patients with hypertrophiccardiomyopathy.Material and methods. Totally 182 HCMP patients included, of those 103 — men (mean age 59,6±14,6y). Diagnosis of AFwas set using ECG or Holter monitoring of ECG using medical charts with the mentioned anamnesis of AF Results. Paroxysmal or permanent form of AF were found in 60 (33%) patients. AF patients were older (64,2±11,2 vs 57,3±15,6 y, p=0,005), with more significant symptomatics(CHFFCbyNYHA2,4±0,8vs2,1±0,8, p=0,02). In AF patients the size of left atrium (LA) was larger than in sinus patients (4,5±0,6 vs 4,1±0,7 cm, p=0,00003). Prevalence of outgoing tract of the left ventricle (OTLV) was nearly same in both groups (50% vs 52,2%, p=0,2), and maximum pressure gradient (PGmax) in OTLV was higher in AF patients (46,0±48,0 vs 21,8±26,6 mmHg, p=0,02). There is and increase of AF with the age (r=0,21, p=0,005), severity of symptoms (r=0,2, p=0,001), LAenlargement(r=0,44, p=0,04), severity of pulmonary hypertension (r=0,47, p=0,004), value of PGmax in OTLV (r=0,23, p=0,02). With the method of binary logistic regression 3 main variables were selected as the most of predictable value for AF: age, LA size, PGmax in OTLV. The model defined that makes to estimate the risk of AF with high diagnostic probability — x 22,0, df=3 (p=0,00006): AF = 0,05307 * age + 0,98065 * LA + 0,01516 * Рймакс in OTLV - 8,66. With the result >0 there is a high risk of AF, and if <0 — the risk of AF is minimum.Conclusion. The model invented for risk prediction in AF in HCMP patients using three predictors: patient age, left atrium diameter and maximum gradient of pressure in OTLV. |
| first_indexed | 2024-04-09T20:50:05Z |
| format | Article |
| id | doaj.art-948aef529f2245fbb472a372fc00ced5 |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2025-03-14T09:31:13Z |
| publishDate | 2015-05-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-948aef529f2245fbb472a372fc00ced52025-03-02T11:42:36Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202015-05-0105647010.15829/1560-4071-2015-5-64-70316ATRIAL FIBRILLATION AND FLUTTER IN HYPERTROPHIC CARDIOMYOPATHYN. S. Krylova0A. E. Demkina1F. M. Khashieva2E. A. Kovalevskaya3N. G. Poteshkina4ГБОУ ВПО Российский национальный исследовательский медицинский университет имени Н. И. Пирогова МЗ РФ; ГБУЗ Городская клиническая больница № 52 Департамента здравоохранения г. Москвы, Москва, Россия.SBEI HPE Russian National Research Medical University n.a. N.I. Pirogov of HMSBEI HPE Russian National Research Medical University n.a. N.I. Pirogov of HMSBEI HPE Russian National Research Medical University n.a. N.I. Pirogov of HM; SBHI City Clinical Hospital №52 of Healthcare Department of Moscow, Moscow, Russia.SBEI HPE Russian National Research Medical University n.a. N.I. Pirogov of HMAim. To find out the factors associated with atrial fibrillation/flutter (AF) in patients with hypertrophiccardiomyopathy.Material and methods. Totally 182 HCMP patients included, of those 103 — men (mean age 59,6±14,6y). Diagnosis of AFwas set using ECG or Holter monitoring of ECG using medical charts with the mentioned anamnesis of AF Results. Paroxysmal or permanent form of AF were found in 60 (33%) patients. AF patients were older (64,2±11,2 vs 57,3±15,6 y, p=0,005), with more significant symptomatics(CHFFCbyNYHA2,4±0,8vs2,1±0,8, p=0,02). In AF patients the size of left atrium (LA) was larger than in sinus patients (4,5±0,6 vs 4,1±0,7 cm, p=0,00003). Prevalence of outgoing tract of the left ventricle (OTLV) was nearly same in both groups (50% vs 52,2%, p=0,2), and maximum pressure gradient (PGmax) in OTLV was higher in AF patients (46,0±48,0 vs 21,8±26,6 mmHg, p=0,02). There is and increase of AF with the age (r=0,21, p=0,005), severity of symptoms (r=0,2, p=0,001), LAenlargement(r=0,44, p=0,04), severity of pulmonary hypertension (r=0,47, p=0,004), value of PGmax in OTLV (r=0,23, p=0,02). With the method of binary logistic regression 3 main variables were selected as the most of predictable value for AF: age, LA size, PGmax in OTLV. The model defined that makes to estimate the risk of AF with high diagnostic probability — x 22,0, df=3 (p=0,00006): AF = 0,05307 * age + 0,98065 * LA + 0,01516 * Рймакс in OTLV - 8,66. With the result >0 there is a high risk of AF, and if <0 — the risk of AF is minimum.Conclusion. The model invented for risk prediction in AF in HCMP patients using three predictors: patient age, left atrium diameter and maximum gradient of pressure in OTLV.https://russjcardiol.elpub.ru/jour/article/view/316hypertrophic cardiomyopathyatrial fibrillationleft ventricle outgoing tract obstruction. |
| spellingShingle | N. S. Krylova A. E. Demkina F. M. Khashieva E. A. Kovalevskaya N. G. Poteshkina ATRIAL FIBRILLATION AND FLUTTER IN HYPERTROPHIC CARDIOMYOPATHY Российский кардиологический журнал hypertrophic cardiomyopathy atrial fibrillation left ventricle outgoing tract obstruction. |
| title | ATRIAL FIBRILLATION AND FLUTTER IN HYPERTROPHIC CARDIOMYOPATHY |
| title_full | ATRIAL FIBRILLATION AND FLUTTER IN HYPERTROPHIC CARDIOMYOPATHY |
| title_fullStr | ATRIAL FIBRILLATION AND FLUTTER IN HYPERTROPHIC CARDIOMYOPATHY |
| title_full_unstemmed | ATRIAL FIBRILLATION AND FLUTTER IN HYPERTROPHIC CARDIOMYOPATHY |
| title_short | ATRIAL FIBRILLATION AND FLUTTER IN HYPERTROPHIC CARDIOMYOPATHY |
| title_sort | atrial fibrillation and flutter in hypertrophic cardiomyopathy |
| topic | hypertrophic cardiomyopathy atrial fibrillation left ventricle outgoing tract obstruction. |
| url | https://russjcardiol.elpub.ru/jour/article/view/316 |
| work_keys_str_mv | AT nskrylova atrialfibrillationandflutterinhypertrophiccardiomyopathy AT aedemkina atrialfibrillationandflutterinhypertrophiccardiomyopathy AT fmkhashieva atrialfibrillationandflutterinhypertrophiccardiomyopathy AT eakovalevskaya atrialfibrillationandflutterinhypertrophiccardiomyopathy AT ngpoteshkina atrialfibrillationandflutterinhypertrophiccardiomyopathy |