Multi-Mode Lanthanide-Doped Ratiometric Luminescent Nanothermometer for Near-Infrared Imaging within Biological Windows
Owing to its high reliability and accuracy, the ratiometric luminescent thermometer can provide non-contact and fast temperature measurements. In particular, the nanomaterials doped with lanthanide ions can achieve multi-mode luminescence and temperature measurement by modifying the type of doped io...
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| Format: | Article |
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MDPI AG
2023-01-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/13/1/219 |
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| author | Hao Li Esmaeil Heydari Yinyan Li Hui Xu Shiqing Xu Liang Chen Gongxun Bai |
| author_facet | Hao Li Esmaeil Heydari Yinyan Li Hui Xu Shiqing Xu Liang Chen Gongxun Bai |
| author_sort | Hao Li |
| collection | DOAJ |
| description | Owing to its high reliability and accuracy, the ratiometric luminescent thermometer can provide non-contact and fast temperature measurements. In particular, the nanomaterials doped with lanthanide ions can achieve multi-mode luminescence and temperature measurement by modifying the type of doped ions and excitation light source. The better penetration of the near-infrared (NIR) photons can assist bio-imaging and replace thermal vision cameras for photothermal imaging. In this work, we prepared core–shell cubic phase nanomaterials doped with lanthanide ions, with Ba<sub>2</sub>LuF<sub>7</sub> doped with Er<sup>3+</sup>/Yb<sup>3+</sup>/Nd<sup>3+</sup> as the core and Ba<sub>2</sub>LaF<sub>7</sub> as the coating shell. The nanoparticles were designed according to the passivation layer to reduce the surface energy loss and enhance the emission intensity. Green upconversion luminescence can be observed under both 980 nm and 808 nm excitation. A single and strong emission band can be obtained under 980 nm excitation, while abundant and weak emission bands appear under 808 nm excitation. Meanwhile, multi-mode ratiometric optical thermometers were achieved by selecting different emission peaks in the NIR window under 808 nm excitation for non-contact temperature measurement at different tissue depths. The results suggest that our core–shell NIR nanoparticles can be used to assist bio-imaging and record temperature for biomedicine. |
| first_indexed | 2024-03-09T09:43:46Z |
| format | Article |
| id | doaj.art-948e55367c3e45778afbbf99ebae8afa |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-09T09:43:46Z |
| publishDate | 2023-01-01 |
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| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-948e55367c3e45778afbbf99ebae8afa2023-12-02T00:45:18ZengMDPI AGNanomaterials2079-49912023-01-0113121910.3390/nano13010219Multi-Mode Lanthanide-Doped Ratiometric Luminescent Nanothermometer for Near-Infrared Imaging within Biological WindowsHao Li0Esmaeil Heydari1Yinyan Li2Hui Xu3Shiqing Xu4Liang Chen5Gongxun Bai6Key Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, China Jiliang University, Hangzhou 310018, ChinaNanophotonic Sensors & Optofluidics Lab., Faculty of Physics, Kharazmi University, Tehran 15719-14911, IranKey Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, China Jiliang University, Hangzhou 310018, ChinaKey Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, China Jiliang University, Hangzhou 310018, ChinaKey Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, China Jiliang University, Hangzhou 310018, ChinaKey Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, China Jiliang University, Hangzhou 310018, ChinaKey Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, China Jiliang University, Hangzhou 310018, ChinaOwing to its high reliability and accuracy, the ratiometric luminescent thermometer can provide non-contact and fast temperature measurements. In particular, the nanomaterials doped with lanthanide ions can achieve multi-mode luminescence and temperature measurement by modifying the type of doped ions and excitation light source. The better penetration of the near-infrared (NIR) photons can assist bio-imaging and replace thermal vision cameras for photothermal imaging. In this work, we prepared core–shell cubic phase nanomaterials doped with lanthanide ions, with Ba<sub>2</sub>LuF<sub>7</sub> doped with Er<sup>3+</sup>/Yb<sup>3+</sup>/Nd<sup>3+</sup> as the core and Ba<sub>2</sub>LaF<sub>7</sub> as the coating shell. The nanoparticles were designed according to the passivation layer to reduce the surface energy loss and enhance the emission intensity. Green upconversion luminescence can be observed under both 980 nm and 808 nm excitation. A single and strong emission band can be obtained under 980 nm excitation, while abundant and weak emission bands appear under 808 nm excitation. Meanwhile, multi-mode ratiometric optical thermometers were achieved by selecting different emission peaks in the NIR window under 808 nm excitation for non-contact temperature measurement at different tissue depths. The results suggest that our core–shell NIR nanoparticles can be used to assist bio-imaging and record temperature for biomedicine.https://www.mdpi.com/2079-4991/13/1/219fluoride nanocrystalsratiometric thermometrylanthanide dopantupconversionphotothermal therapy |
| spellingShingle | Hao Li Esmaeil Heydari Yinyan Li Hui Xu Shiqing Xu Liang Chen Gongxun Bai Multi-Mode Lanthanide-Doped Ratiometric Luminescent Nanothermometer for Near-Infrared Imaging within Biological Windows Nanomaterials fluoride nanocrystals ratiometric thermometry lanthanide dopant upconversion photothermal therapy |
| title | Multi-Mode Lanthanide-Doped Ratiometric Luminescent Nanothermometer for Near-Infrared Imaging within Biological Windows |
| title_full | Multi-Mode Lanthanide-Doped Ratiometric Luminescent Nanothermometer for Near-Infrared Imaging within Biological Windows |
| title_fullStr | Multi-Mode Lanthanide-Doped Ratiometric Luminescent Nanothermometer for Near-Infrared Imaging within Biological Windows |
| title_full_unstemmed | Multi-Mode Lanthanide-Doped Ratiometric Luminescent Nanothermometer for Near-Infrared Imaging within Biological Windows |
| title_short | Multi-Mode Lanthanide-Doped Ratiometric Luminescent Nanothermometer for Near-Infrared Imaging within Biological Windows |
| title_sort | multi mode lanthanide doped ratiometric luminescent nanothermometer for near infrared imaging within biological windows |
| topic | fluoride nanocrystals ratiometric thermometry lanthanide dopant upconversion photothermal therapy |
| url | https://www.mdpi.com/2079-4991/13/1/219 |
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