KAP1 is a Novel Substrate for the Arginine Methyltransferase PRMT5

KAP1 is a Novel Substrate for the Arginine Methyltransferase PRMT5

KRAB-associated protein 1 (KAP1), the transcriptional corepressor of Kruppel-associated box zinc finger proteins (KRAB-ZFPs), is subjected to multiple post-translational modifications that are involved in fine-tuning of the multiple biological functions of KAP1. In previous papers, we analyzed the...

Full description

Bibliographic Details
Main Authors:	Roberta di Caprio, Michela Ciano, Giorgia Montano, Paola Costanzo, Elena Cesaro
Format:	Article
Language:	English
Published:	MDPI AG 2015-01-01
Series:	Biology
Subjects:	KRAB-associated protein 1 (KAP1) protein-protein interaction post-translational modifications protein arginine methyltransferase
Online Access:	http://www.mdpi.com/2079-7737/4/1/41

Similar Items

Discovery of a potent and dual-selective bisubstrate inhibitor for protein arginine methyltransferase 4/5
by: Ayad A. Al-Hamashi, et al.
Published: (2021-09-01)

A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing
by: Zangger Nadine, et al.
Published: (2011-07-01)

A Pan-Inhibitor for Protein Arginine Methyltransferase Family Enzymes
by: Iredia D. Iyamu, et al.
Published: (2021-06-01)

The Role of Protein Arginine Methyltransferases in DNA Damage Response
by: Charles Brobbey, et al.
Published: (2022-08-01)

Protein arginine methyltransferases and hepatocellular carcinoma: A review
by: Yu Lei, et al.
Published: (2021-11-01)

Protein Arginine Methyltransferase 5 (PRMT5) Inhibitors in Oncology Clinical Trials: A review
by: Kavanya Feustel, et al.
Published: (2022-08-01)

The emerging roles of protein arginine methyltransferases in antiviral innate immune signaling pathways
by: Hui Nie, et al.
Published: (2023-12-01)

Protein arginine methyltransferases in renal development, injury, repair, and fibrosis
by: Jianjun Yu, et al.
Published: (2023-02-01)

The protein arginine methyltransferase PRMT1 promotes TBK1 activation through asymmetric arginine methylation
by: Zhenzhen Yan, et al.
Published: (2021-09-01)

Protein Arginine Methyltransferase 1 (PRMT1) Selective Inhibitor, TC-E 5003, Has Anti-Inflammatory Properties in TLR4 Signaling
by: Eunji Kim, et al.
Published: (2020-04-01)

Entamoeba histolytica: protein arginine transferase 1a methylates arginine residues and potentially modify the H4 histone
by: Jessica Borbolla-Vázquez, et al.
Published: (2015-04-01)

Protein Arginine Methyltransferase 4 Regulates Adipose Tissue Lipolysis in Type 1 Diabetic Mice
by: Li Y, et al.
Published: (2020-02-01)

ZNF224 Protein: Multifaceted Functions Based on Its Molecular Partners
by: Elena Cesaro, et al.
Published: (2021-10-01)

Expression of chemical modification enzymes PADs and PRMTs targeting protein arginine residues in human hepatocellular carcinoma cell lines
by: ZOU Jin, HE Xianglei, ZHANG Xin, CHEN Riping, ZHANG Yu, HU Shuaiyue, YING Shibo
Published: (2023-06-01)

Structure and Function of Protein Arginine Methyltransferase PRMT7
by: Levon Halabelian, et al.
Published: (2021-07-01)

Structure, Activity and Function of the PRMT2 Protein Arginine Methyltransferase
by: Vincent Cura, et al.
Published: (2021-11-01)

Integrative Evaluation of the Clinical Significance Underlying Protein Arginine Methyltransferases in Hepatocellular Carcinoma
by: Yikun Jiang, et al.
Published: (2023-08-01)

Protein Arginine Methyltransferases in Pancreatic Ductal Adenocarcinoma: New Molecular Targets for Therapy
by: Kritisha Bhandari, et al.
Published: (2024-04-01)

Regulation of Skeletal Muscle Plasticity by Protein Arginine Methyltransferases and Their Potential Roles in Neuromuscular Disorders
by: Derek W. Stouth, et al.
Published: (2017-11-01)

Arginine Methyltransferases Are Regulated by Epstein-Barr Virus in B Cells and Are Differentially Expressed in Hodgkin’s Lymphoma
by: Sarah Leonard, et al.
Published: (2012-09-01)

KAP1 phosphorylation promotes the survival of neural stem cells after ischemia/reperfusion by maintaining the stability of PCNA
by: Wan Wang, et al.
Published: (2022-07-01)

The protein arginine methyltransferase family (PRMTs) regulates metastases in various tumors: From experimental study to clinical application
by: Jiaoyang Ning, et al.
Published: (2023-11-01)

Integrin αvβ3 Engagement Regulates Glucose Metabolism and Migration through Focal Adhesion Kinase (FAK) and Protein Arginine Methyltransferase 5 (PRMT5) in Glioblastoma Cells
by: Pulin Che, et al.
Published: (2021-03-01)

Protein methyltransferases /
by: Clarke, Steven G., et al.
Published: (2006)

Flavokawain A is a natural inhibitor of PRMT5 in bladder cancer
by: Shuangjie Liu, et al.
Published: (2022-10-01)

The Protein Arginine Methyltransferase PRMT-5 Regulates SER-2 Tyramine Receptor-Mediated Behaviors in Caenorhabditis elegans
by: Alexander Bowitch, et al.
Published: (2018-07-01)

PRMT1 Integrates Immune Microenvironment and Fatty Acid Metabolism Response in Progression of Hepatocellular Carcinoma
by: Yan J, et al.
Published: (2024-01-01)

PRMT1 Promoted HCC Growth and Metastasis In Vitro and In Vivo via Activating the STAT3 Signalling Pathway
by: Xiu-Ping Zhang, et al.
Published: (2018-06-01)

SRSF3 and HNRNPH1 Regulate Radiation-Induced Alternative Splicing of Protein Arginine Methyltransferase 5 in Hepatocellular Carcinoma
by: Chaowei Wen, et al.
Published: (2022-11-01)

Correlation of SRSF1 and PRMT1 expression with clinical status of pediatric acute lymphoblastic leukemia
by: Zou Limin, et al.
Published: (2012-07-01)

Arginine methylation as a key post-translational modification in skeletal muscle homeostasis: a review
by: Hyebeen Kim, et al.
Published: (2019-12-01)

Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer
by: Ming-Chuan Hsu, et al.
Published: (2019-07-01)

Global analysis of protein arginine methylation
by: Fangrong Zhang, et al.
Published: (2021-06-01)

Cingulate protein arginine methyltransferases 1 regulates peripheral hypersensitivity via fragile X messenger ribonucleoprotein
by: Cheng Wu, et al.
Published: (2023-04-01)

Huntingtin-mediated axonal transport requires arginine methylation by PRMT6
by: Alice Migazzi, et al.
Published: (2021-04-01)

Genome-Wide Identification of Maize Protein Arginine Methyltransferase Genes and Functional Analysis of <i>ZmPRMT1</i> Reveal Essential Roles in <i>Arabidopsis</i> Flowering Regulation and Abiotic Stress Tolerance
by: Qiqi Ling, et al.
Published: (2022-10-01)

Inhibition of PRMT1 alleviates sepsis‐induced acute kidney injury in mice by blocking the TGF‐β1 and IL‐6 trans‐signaling pathways
by: Yu Zhu, et al.
Published: (2023-10-01)

The Role and Mechanism of Lysine Methyltransferase and Arginine Methyltransferase in Kidney Diseases
by: Xun Zhou, et al.
Published: (2022-04-01)

Protein Arginine Methylation: An Emerging Modification in Cancer Immunity and Immunotherapy
by: Weijing Dai, et al.
Published: (2022-04-01)

Arginine Methyltransferase PeRmtC Regulates Development and Pathogenicity of <i>Penicillium</i> <i>expansum</i> via Mediating Key Genes in Conidiation and Secondary Metabolism
by: Xiaodi Xu, et al.
Published: (2021-09-01)