Control of neural crest multipotency by Wnt signaling and the Lin28/let-7 axis
A crucial step in cell differentiation is the silencing of developmental programs underlying multipotency. While much is known about how lineage-specific genes are activated to generate distinct cell types, the mechanisms driving suppression of stemness are far less understood. To address this, we e...
Main Authors: | Debadrita Bhattacharya, Megan Rothstein, Ana Paula Azambuja, Marcos Simoes-Costa |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/40556 |
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