Control of neural crest multipotency by Wnt signaling and the Lin28/let-7 axis

A crucial step in cell differentiation is the silencing of developmental programs underlying multipotency. While much is known about how lineage-specific genes are activated to generate distinct cell types, the mechanisms driving suppression of stemness are far less understood. To address this, we e...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Debadrita Bhattacharya, Megan Rothstein, Ana Paula Azambuja, Marcos Simoes-Costa
Format: Artikel
Sprache:English
Veröffentlicht: eLife Sciences Publications Ltd 2018-12-01
Schriftenreihe:eLife
Schlagworte:
Online Zugang:https://elifesciences.org/articles/40556