Control of neural crest multipotency by Wnt signaling and the Lin28/let-7 axis

A crucial step in cell differentiation is the silencing of developmental programs underlying multipotency. While much is known about how lineage-specific genes are activated to generate distinct cell types, the mechanisms driving suppression of stemness are far less understood. To address this, we e...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Debadrita Bhattacharya, Megan Rothstein, Ana Paula Azambuja, Marcos Simoes-Costa
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: eLife Sciences Publications Ltd 2018-12-01
Sraith:eLife
Ábhair:
Rochtain ar líne:https://elifesciences.org/articles/40556