miR-29b and miR-29c are involved in Toll-like receptor control of glucocorticoid-induced apoptosis in human plasmacytoid dendritic cells.

miR-29b and miR-29c are involved in Toll-like receptor control of glucocorticoid-induced apoptosis in human plasmacytoid dendritic cells.

Glucocorticoids (GCs) are frequently used to treat many of the acute disease manifestations associated with inflammatory and autoimmune disorders. However, Toll-like receptor (TLR) pathway-activated plasmacytoid dendritic cells (pDCs) are resistant to GC-induced apoptosis, which leads to the ineffic...

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Bibliographic Details
Main Authors: Yongfeng Hong, Jianxian Wu, Jingpu Zhao, Huiping Wang, Yi Liu, Tianping Chen, Xiuli Kan, Qianshan Tao, Xianshan Shen, Kaili Yan, Zhimin Zhai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3720938?pdf=render

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