The Durability and Efficacy of Cryopreserved Human Umbilical Cord Tissue Allograft for the Supplementation of Cartilage Defects Associated with the Sacroiliac Joint: A Case Series
This Institutional Review Board (IRB)-approved retrospective observational protocol aims to report the safety and efficacy of birth tissue allografts applied in 38 patients with treatment-resistant sacroiliac (SI) joint pain. The research methodology consisted of an observational recording of the Nu...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Reports |
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| Online Access: | https://www.mdpi.com/2571-841X/6/1/12 |
| _version_ | 1797609141367209984 |
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| author | Albert Lai Jon Shou Steve A. Traina Tyler Barrett |
| author_facet | Albert Lai Jon Shou Steve A. Traina Tyler Barrett |
| author_sort | Albert Lai |
| collection | DOAJ |
| description | This Institutional Review Board (IRB)-approved retrospective observational protocol aims to report the safety and efficacy of birth tissue allografts applied in 38 patients with treatment-resistant sacroiliac (SI) joint pain. The research methodology consisted of an observational recording of the Numeric Pain Rating Scale (NPRS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC), which measure pain, stiffness, and physical function. No adverse events or adverse reactions were observed in the 38 patients. Statistically significant improvements in NPRS and WOMAC scores of the affected SI joint were reported after 90 days. The observational data suggests that Wharton’s jelly allograft applications are safe, minimally invasive, and efficacious. They may present an alternative to surgery for patients who fail conservative and procedural management of pain originating from chondral cartilage degeneration of the SI joint. |
| first_indexed | 2024-03-11T05:57:25Z |
| format | Article |
| id | doaj.art-949df35eac1f457a9affb8b175c97931 |
| institution | Directory Open Access Journal |
| issn | 2571-841X |
| language | English |
| last_indexed | 2024-03-11T05:57:25Z |
| publishDate | 2023-03-01 |
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| series | Reports |
| spelling | doaj.art-949df35eac1f457a9affb8b175c979312023-11-17T13:41:10ZengMDPI AGReports2571-841X2023-03-01611210.3390/reports6010012The Durability and Efficacy of Cryopreserved Human Umbilical Cord Tissue Allograft for the Supplementation of Cartilage Defects Associated with the Sacroiliac Joint: A Case SeriesAlbert Lai0Jon Shou1Steve A. Traina2Tyler Barrett3Desert Pain Specialists, 72780 Country Club Drive, #C-300, Rancho Mirage, CA 92270, USARegenative Labs, 1700 W Main Street, Pensacola, FL 32502, USAWestern Orthopedics, 1830 Franklin Street, 450, Denver, CO 80218, USARegenative Labs, 1700 W Main Street, Pensacola, FL 32502, USAThis Institutional Review Board (IRB)-approved retrospective observational protocol aims to report the safety and efficacy of birth tissue allografts applied in 38 patients with treatment-resistant sacroiliac (SI) joint pain. The research methodology consisted of an observational recording of the Numeric Pain Rating Scale (NPRS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC), which measure pain, stiffness, and physical function. No adverse events or adverse reactions were observed in the 38 patients. Statistically significant improvements in NPRS and WOMAC scores of the affected SI joint were reported after 90 days. The observational data suggests that Wharton’s jelly allograft applications are safe, minimally invasive, and efficacious. They may present an alternative to surgery for patients who fail conservative and procedural management of pain originating from chondral cartilage degeneration of the SI joint.https://www.mdpi.com/2571-841X/6/1/12Wharton’s jellyregenerative medicinesacroiliac joint dysfunctioncartilage defects |
| spellingShingle | Albert Lai Jon Shou Steve A. Traina Tyler Barrett The Durability and Efficacy of Cryopreserved Human Umbilical Cord Tissue Allograft for the Supplementation of Cartilage Defects Associated with the Sacroiliac Joint: A Case Series Reports Wharton’s jelly regenerative medicine sacroiliac joint dysfunction cartilage defects |
| title | The Durability and Efficacy of Cryopreserved Human Umbilical Cord Tissue Allograft for the Supplementation of Cartilage Defects Associated with the Sacroiliac Joint: A Case Series |
| title_full | The Durability and Efficacy of Cryopreserved Human Umbilical Cord Tissue Allograft for the Supplementation of Cartilage Defects Associated with the Sacroiliac Joint: A Case Series |
| title_fullStr | The Durability and Efficacy of Cryopreserved Human Umbilical Cord Tissue Allograft for the Supplementation of Cartilage Defects Associated with the Sacroiliac Joint: A Case Series |
| title_full_unstemmed | The Durability and Efficacy of Cryopreserved Human Umbilical Cord Tissue Allograft for the Supplementation of Cartilage Defects Associated with the Sacroiliac Joint: A Case Series |
| title_short | The Durability and Efficacy of Cryopreserved Human Umbilical Cord Tissue Allograft for the Supplementation of Cartilage Defects Associated with the Sacroiliac Joint: A Case Series |
| title_sort | durability and efficacy of cryopreserved human umbilical cord tissue allograft for the supplementation of cartilage defects associated with the sacroiliac joint a case series |
| topic | Wharton’s jelly regenerative medicine sacroiliac joint dysfunction cartilage defects |
| url | https://www.mdpi.com/2571-841X/6/1/12 |
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