Carpal tunnel syndrome caused by tophi deposited under the epineurium of the median nerve: A case report

IntroductionUsually caused by compression of the wrist's median nerve, carpal tunnel syndrome (CTS) is one of the most common types of peripheral neuropathy. Tophi deposited under the epineurium of the median nerve compress the median nerve, leading to CTS, which is very rare.Case presentationW...

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Main Authors: Wenzhong Zhang, Qingbo Feng, Jiaxiang Gu, Hongjun Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Surgery
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2022.942062/full
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author Wenzhong Zhang
Qingbo Feng
Jiaxiang Gu
Hongjun Liu
author_facet Wenzhong Zhang
Qingbo Feng
Jiaxiang Gu
Hongjun Liu
author_sort Wenzhong Zhang
collection DOAJ
description IntroductionUsually caused by compression of the wrist's median nerve, carpal tunnel syndrome (CTS) is one of the most common types of peripheral neuropathy. Tophi deposited under the epineurium of the median nerve compress the median nerve, leading to CTS, which is very rare.Case presentationWe report a 64-year-old man with a history of tophaceous gout who presented with typical CTS symptoms and was admitted to our hospital. A physical examination revealed swelling over the right volar aspect of the carpal region, and he was unable to flex due to subcutaneous rigidity. Tinel's sign and Phalen's maneuver were positive. Electrophysiological studies confirmed the diagnosis of CTS. A carpal tunnel release and surgery to remove the gouty tophus of the right wrist were performed when serum uric acid levels were within normal limits (5.8 mg/dl). During the operation, tophi deposited under the epineurium of the median nerve were found, and the tophi were completely removed. Operative findings confirmed the diagnosis of CTS due to gout. The patient recovered uneventfully without signs of recurrence of gout and CTS symptoms during a 1-year follow-up period.ConclusionA gouty tophus is an uncommon cause of CTS, and CTS may be caused by gouty tophi if there is evidence of extrinsic compression of the median nerve or symptoms emanating from the carpal tunnel.
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spelling doaj.art-949edb25d1b94baa829de3d90c1239532023-01-06T18:03:19ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2023-01-01910.3389/fsurg.2022.942062942062Carpal tunnel syndrome caused by tophi deposited under the epineurium of the median nerve: A case reportWenzhong Zhang0Qingbo Feng1Jiaxiang Gu2Hongjun Liu3Department of Hand and Foot Surgery, Northern Jiangsu People's Hospital, Clinic Medical College of Yangzhou University, Yangzhou, ChinaDepartment of Liver Surgery and Liver Transplantation Centre, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Hand and Foot Surgery, Northern Jiangsu People's Hospital, Clinic Medical College of Yangzhou University, Yangzhou, ChinaDepartment of Hand and Foot Surgery, Northern Jiangsu People's Hospital, Clinic Medical College of Yangzhou University, Yangzhou, ChinaIntroductionUsually caused by compression of the wrist's median nerve, carpal tunnel syndrome (CTS) is one of the most common types of peripheral neuropathy. Tophi deposited under the epineurium of the median nerve compress the median nerve, leading to CTS, which is very rare.Case presentationWe report a 64-year-old man with a history of tophaceous gout who presented with typical CTS symptoms and was admitted to our hospital. A physical examination revealed swelling over the right volar aspect of the carpal region, and he was unable to flex due to subcutaneous rigidity. Tinel's sign and Phalen's maneuver were positive. Electrophysiological studies confirmed the diagnosis of CTS. A carpal tunnel release and surgery to remove the gouty tophus of the right wrist were performed when serum uric acid levels were within normal limits (5.8 mg/dl). During the operation, tophi deposited under the epineurium of the median nerve were found, and the tophi were completely removed. Operative findings confirmed the diagnosis of CTS due to gout. The patient recovered uneventfully without signs of recurrence of gout and CTS symptoms during a 1-year follow-up period.ConclusionA gouty tophus is an uncommon cause of CTS, and CTS may be caused by gouty tophi if there is evidence of extrinsic compression of the median nerve or symptoms emanating from the carpal tunnel.https://www.frontiersin.org/articles/10.3389/fsurg.2022.942062/fullcarpal tunnel syndromegouthyperuricemiasurgerytophicase report
spellingShingle Wenzhong Zhang
Qingbo Feng
Jiaxiang Gu
Hongjun Liu
Carpal tunnel syndrome caused by tophi deposited under the epineurium of the median nerve: A case report
Frontiers in Surgery
carpal tunnel syndrome
gout
hyperuricemia
surgery
tophi
case report
title Carpal tunnel syndrome caused by tophi deposited under the epineurium of the median nerve: A case report
title_full Carpal tunnel syndrome caused by tophi deposited under the epineurium of the median nerve: A case report
title_fullStr Carpal tunnel syndrome caused by tophi deposited under the epineurium of the median nerve: A case report
title_full_unstemmed Carpal tunnel syndrome caused by tophi deposited under the epineurium of the median nerve: A case report
title_short Carpal tunnel syndrome caused by tophi deposited under the epineurium of the median nerve: A case report
title_sort carpal tunnel syndrome caused by tophi deposited under the epineurium of the median nerve a case report
topic carpal tunnel syndrome
gout
hyperuricemia
surgery
tophi
case report
url https://www.frontiersin.org/articles/10.3389/fsurg.2022.942062/full
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AT qingbofeng carpaltunnelsyndromecausedbytophidepositedundertheepineuriumofthemediannerveacasereport
AT jiaxianggu carpaltunnelsyndromecausedbytophidepositedundertheepineuriumofthemediannerveacasereport
AT hongjunliu carpaltunnelsyndromecausedbytophidepositedundertheepineuriumofthemediannerveacasereport