The Impact of MicroRNAs during Inflammatory Bowel Disease: Effects on the Mucus Layer and Intercellular Junctions for Gut Permeability

The Impact of MicroRNAs during Inflammatory Bowel Disease: Effects on the Mucus Layer and Intercellular Junctions for Gut Permeability

Research on inflammatory bowel disease (IBD) has produced mounting evidence for the modulation of microRNAs (miRNAs) during pathogenesis. MiRNAs are small, non-coding RNAs that interfere with the translation of mRNAs. Their high stability in free circulation at various regions of the body allows res...

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Bibliographic Details
Main Authors: Sarah Stiegeler, Kevin Mercurio, Miruna Alexandra Iancu, Sinéad C. Corr
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
microRNAs
inflammatory bowel disease
gut epithelial barrier
mucus layer
intercellular junctions
Online Access:https://www.mdpi.com/2073-4409/10/12/3358

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