Systematic analysis based on the cuproptosis-related genes identifies ferredoxin 1 as an immune regulator and therapeutic target for glioblastoma

Systematic analysis based on the cuproptosis-related genes identifies ferredoxin 1 as an immune regulator and therapeutic target for glioblastoma

Abstract Glioblastoma multiforme (GBM) is recognized as the prevailing malignant and aggressive primary brain tumor, characterized by an exceedingly unfavorable prognosis. Cuproptosis, a recently identified form of programmed cell death, exhibits a strong association with cancer progression, therape...

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Bibliographic Details
Main Authors: Lirui Dai, Peizhi Zhou, Liang Lyu, Shu Jiang
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Cancer
Subjects:
Glioblastoma
Cuproptosis
Prognostic model
Drug
FDX1
Immune infiltration
Online Access:https://doi.org/10.1186/s12885-023-11727-z

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