Population pharmacokinetics and exposure–response analyses of polatuzumab vedotin in patients with previously untreated DLBCL from the POLARIX study
Abstract Polatuzumab vedotin is a CD79b‐directed antibody–drug conjugate that targets B cells and delivers the cytotoxic payload monomethyl auristatin E (MMAE). The phase III POLARIX study (NCT03274492) evaluated polatuzumab vedotin in combination with rituximab, cyclophosphamide, doxorubicin, and p...
主要な著者: | , , , , , , , , , , , , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
Wiley
2024-06-01
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シリーズ: | CPT: Pharmacometrics & Systems Pharmacology |
オンライン・アクセス: | https://doi.org/10.1002/psp4.13141 |