Metabolism of the Flavonol Kaempferol in Kidney Cells Liberates the B-ring to Enter Coenzyme Q Biosynthesis

Metabolism of the Flavonol Kaempferol in Kidney Cells Liberates the B-ring to Enter Coenzyme Q Biosynthesis

Coenzyme Q (CoQ) is an essential component of the mitochondrial electron transport chain and an important antioxidant present in all cellular membranes. CoQ deficiencies are frequent in aging and in age-related diseases, and current treatments are limited to CoQ supplementation. Strategies that rely...

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Bibliographic Details
Main Authors: Lucía Fernández-del-Río, Eric Soubeyrand, Gilles J. Basset, Catherine F. Clarke
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
flavonoids
flavonol
kaempferol
coenzyme Q
kidney cells
precursor
Online Access:https://www.mdpi.com/1420-3049/25/13/2955

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