SGK1-Sensitive Regulation of Cyclin-Dependent Kinase Inhibitor 1B (p27) in Cardiomyocyte Hypertrophy

SGK1-Sensitive Regulation of Cyclin-Dependent Kinase Inhibitor 1B (p27) in Cardiomyocyte Hypertrophy

Background/Aims: The serum- and glucocorticoid-inducible kinase SGK1 participates in the orchestration of cardiac hypertrophy and remodeling. Signaling linking SGK1 activity to cardiac remodeling is, however, incompletely understood. SGK1 phosphorylation targets include cyclin-dependent kinase inhib...

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Bibliographic Details
Main Authors: Jakob Voelkl, Tatsiana Castor, Katharina Musculus, Robert Viereck, Sobuj Mia, Martina Feger, Ioana Alesutan, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
p27
Acta1
Isoproterenol
SGK1
Cardiac hypertrophy
HL-1 cardiomyocytes
Online Access:http://www.karger.com/Article/FullText/430380

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