Adjunctive Techniques for Repair of Ischaemic Mitral Regurgitation

Ischaemic mitral regurgitation is a complex process with debate in the literature as to the optimal treatment pathway. Multiple therapies are available to alleviate mitral regurgitation including medical management, transcatheter edge-to-edge repair, mitral valve repair and mitral valve replacement....

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Main Authors: Sigrid L Johannesen, Colin M Barker, Melissa M Levack
Format: Article
Language:English
Published: Radcliffe Medical Media 2021-12-01
Series:Cardiac Failure Review
Online Access:https://www.cfrjournal.com/articleindex/cfr.2021.06
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author Sigrid L Johannesen
Colin M Barker
Melissa M Levack
author_facet Sigrid L Johannesen
Colin M Barker
Melissa M Levack
author_sort Sigrid L Johannesen
collection DOAJ
description Ischaemic mitral regurgitation is a complex process with debate in the literature as to the optimal treatment pathway. Multiple therapies are available to alleviate mitral regurgitation including medical management, transcatheter edge-to-edge repair, mitral valve repair and mitral valve replacement. Medical management with goal-directed therapy should be utilised in patients with heart failure and mild-to-moderate regurgitation. Transcatheter approaches are typically used in patients with prohibitive operative risk, although their use is expanding, especially in those with functional mitral regurgitation who are not responding to goal-directed medical therapy. It is generally accepted that patients with mild-to-moderate disease can avoid valve intervention if successful revascularisation is performed. A higher consideration should be given to valve replacement over repair in patients with severe mitral regurgitation in the setting of myocardial ischaemia. Operative course must be personalised to each patient, and continues to develop with improving technologies and ongoing research into optimal treatment.
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spelling doaj.art-94a6af4efb344b41b01a5cf4ef2dac432024-04-20T16:02:31ZengRadcliffe Medical MediaCardiac Failure Review2057-75402057-75592021-12-01710.15420/cfr.2021.06Adjunctive Techniques for Repair of Ischaemic Mitral RegurgitationSigrid L Johannesen0Colin M Barker1Melissa M Levack2Department of Cardiothoracic Surgery, Vanderbilt University Medical Centre, Nashville, TN, USSection of Interventional Cardiology, Vanderbilt University Medical Centre, Nashville, TN, USDepartment of Cardiac Surgery, Vanderbilt University Medical Centre, Nashville, TN, USIschaemic mitral regurgitation is a complex process with debate in the literature as to the optimal treatment pathway. Multiple therapies are available to alleviate mitral regurgitation including medical management, transcatheter edge-to-edge repair, mitral valve repair and mitral valve replacement. Medical management with goal-directed therapy should be utilised in patients with heart failure and mild-to-moderate regurgitation. Transcatheter approaches are typically used in patients with prohibitive operative risk, although their use is expanding, especially in those with functional mitral regurgitation who are not responding to goal-directed medical therapy. It is generally accepted that patients with mild-to-moderate disease can avoid valve intervention if successful revascularisation is performed. A higher consideration should be given to valve replacement over repair in patients with severe mitral regurgitation in the setting of myocardial ischaemia. Operative course must be personalised to each patient, and continues to develop with improving technologies and ongoing research into optimal treatment.https://www.cfrjournal.com/articleindex/cfr.2021.06
spellingShingle Sigrid L Johannesen
Colin M Barker
Melissa M Levack
Adjunctive Techniques for Repair of Ischaemic Mitral Regurgitation
Cardiac Failure Review
title Adjunctive Techniques for Repair of Ischaemic Mitral Regurgitation
title_full Adjunctive Techniques for Repair of Ischaemic Mitral Regurgitation
title_fullStr Adjunctive Techniques for Repair of Ischaemic Mitral Regurgitation
title_full_unstemmed Adjunctive Techniques for Repair of Ischaemic Mitral Regurgitation
title_short Adjunctive Techniques for Repair of Ischaemic Mitral Regurgitation
title_sort adjunctive techniques for repair of ischaemic mitral regurgitation
url https://www.cfrjournal.com/articleindex/cfr.2021.06
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