Endoscopic 1½-transseptal approach for pituitary surgery
BackgroundWe previously introduced the one-and-a-half (1½) nostril endoscopic transsphenoidal approach (OETA) to reduce the damage to the nasal structures. Here, we reported the modified approach which is called the endoscopic 1½-transseptal approach (EOTA) for pituitary surgery by combining the OET...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2022.1116408/full |
| _version_ | 1797955365101371392 |
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| author | Zixiang Cong Junhao Zhu Huaiyu Sun Chao Tang Jin Yang Chiyuan Ma |
| author_facet | Zixiang Cong Junhao Zhu Huaiyu Sun Chao Tang Jin Yang Chiyuan Ma |
| author_sort | Zixiang Cong |
| collection | DOAJ |
| description | BackgroundWe previously introduced the one-and-a-half (1½) nostril endoscopic transsphenoidal approach (OETA) to reduce the damage to the nasal structures. Here, we reported the modified approach which is called the endoscopic 1½-transseptal approach (EOTA) for pituitary surgery by combining the OETA and the microscopic transseptal approach to simplify intranasal procedures and protect nasal mucosa. In EOTA, we removed the sellar lesions in a corridor that is composed of the right submucosal space and the anterior left ½ nasal cavity.MethodsWe introduced EOTA with a detailed technical description and preliminary clinical outcomes. A total of 128 patients who underwent EOTA for pituitary surgery from July 2018 to September 2020 were reviewed for evaluation of the safety and efficacy of this approach.ResultsEOTA had a high gross total resection (GTR) rate and a 1ow complication rate. GTR was achieved in 106 (82.8%) patients, with 81.4% for pituitary adenomas and 93.3% for other non-adenomatous lesions. Post-operative complications included 3 patients (2.3%) with postoperative cerebrospinal fluid leak, 3 patients (2.3%) with diabetes insipidus, 5 patients (3.9%) with anterior pituitary insufficiency and 2 patients (1.6%) with meningitis. In addition, EOTA simplified the intranasal procedures, which led to shortened operation time (67.8 minutes). The results of ASK nasal-12, the Lund-Kennedy score, and the odor identification test showed that patients who underwent EOTA recovered quickly after surgery and the nasal cavity returned to the preoperative condition both apparently and physiologically one month after surgery.ConclusionsEOTA is a simple, safe and effective approach for pituitary lesions, which provides not only a sufficient surgical corridor for 2-surgeon/4- or 3-hands technique but also minimally invasive access to the sellar region. |
| first_indexed | 2024-04-10T23:31:57Z |
| format | Article |
| id | doaj.art-94a6cf5535a648d89c8c74b566fca268 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-10T23:31:57Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-94a6cf5535a648d89c8c74b566fca2682023-01-12T04:52:32ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-01-011210.3389/fonc.2022.11164081116408Endoscopic 1½-transseptal approach for pituitary surgeryZixiang Cong0Junhao Zhu1Huaiyu Sun2Chao Tang3Jin Yang4Chiyuan Ma5Department of Neurosurgery, Affiliated Jinling Hospital, Medicine School of Nanjing University, Nanjing, Jiangsu, ChinaDepartment of Neurosurgery, Affiliated Jinling Hospital, Medicine School of Nanjing University, Nanjing, Jiangsu, ChinaDepartment of Neurosurgery, Tiemei General Hospital of Liaoning Province Healthy Industrial Group, Tieling, Liaoning, ChinaDepartment of Neurosurgery, Affiliated Jinling Hospital, Medicine School of Nanjing University, Nanjing, Jiangsu, ChinaDepartment of Neurosurgery, Affiliated Jinling Hospital, Medicine School of Nanjing University, Nanjing, Jiangsu, ChinaDepartment of Neurosurgery, Affiliated Jinling Hospital, Medicine School of Nanjing University, Nanjing, Jiangsu, ChinaBackgroundWe previously introduced the one-and-a-half (1½) nostril endoscopic transsphenoidal approach (OETA) to reduce the damage to the nasal structures. Here, we reported the modified approach which is called the endoscopic 1½-transseptal approach (EOTA) for pituitary surgery by combining the OETA and the microscopic transseptal approach to simplify intranasal procedures and protect nasal mucosa. In EOTA, we removed the sellar lesions in a corridor that is composed of the right submucosal space and the anterior left ½ nasal cavity.MethodsWe introduced EOTA with a detailed technical description and preliminary clinical outcomes. A total of 128 patients who underwent EOTA for pituitary surgery from July 2018 to September 2020 were reviewed for evaluation of the safety and efficacy of this approach.ResultsEOTA had a high gross total resection (GTR) rate and a 1ow complication rate. GTR was achieved in 106 (82.8%) patients, with 81.4% for pituitary adenomas and 93.3% for other non-adenomatous lesions. Post-operative complications included 3 patients (2.3%) with postoperative cerebrospinal fluid leak, 3 patients (2.3%) with diabetes insipidus, 5 patients (3.9%) with anterior pituitary insufficiency and 2 patients (1.6%) with meningitis. In addition, EOTA simplified the intranasal procedures, which led to shortened operation time (67.8 minutes). The results of ASK nasal-12, the Lund-Kennedy score, and the odor identification test showed that patients who underwent EOTA recovered quickly after surgery and the nasal cavity returned to the preoperative condition both apparently and physiologically one month after surgery.ConclusionsEOTA is a simple, safe and effective approach for pituitary lesions, which provides not only a sufficient surgical corridor for 2-surgeon/4- or 3-hands technique but also minimally invasive access to the sellar region.https://www.frontiersin.org/articles/10.3389/fonc.2022.1116408/fullendoscopic transseptal approachone-and-a-half nostril endoscopic transsphenoidal approachpituitary surgerysinonasal quality of lifeskull base |
| spellingShingle | Zixiang Cong Junhao Zhu Huaiyu Sun Chao Tang Jin Yang Chiyuan Ma Endoscopic 1½-transseptal approach for pituitary surgery Frontiers in Oncology endoscopic transseptal approach one-and-a-half nostril endoscopic transsphenoidal approach pituitary surgery sinonasal quality of life skull base |
| title | Endoscopic 1½-transseptal approach for pituitary surgery |
| title_full | Endoscopic 1½-transseptal approach for pituitary surgery |
| title_fullStr | Endoscopic 1½-transseptal approach for pituitary surgery |
| title_full_unstemmed | Endoscopic 1½-transseptal approach for pituitary surgery |
| title_short | Endoscopic 1½-transseptal approach for pituitary surgery |
| title_sort | endoscopic 1 1 2 transseptal approach for pituitary surgery |
| topic | endoscopic transseptal approach one-and-a-half nostril endoscopic transsphenoidal approach pituitary surgery sinonasal quality of life skull base |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2022.1116408/full |
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